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The Molecular Basis of Biological Interactions 1
The Cell Membrane
6 other sections not shown
Academic Press acetylcholine acetylcholinesterase acid Acta action potential activity adrenergic affinity agents agonist alkyl allosteric Amer ammonium analogs anesthetics anionic antagonism antagonists appears atropine Belleau binding sites Biochem Biol biological Biophys Brit Ca++ carbamylcholine catalytic catecholamines cations cell membrane chain Changeux Chapter Chem choline cholinergic receptor cholinomimetic compounds concentration concentration-response curves conformational change constant contractile cyclic AMP D. J. Triggle decamethonium depolarization Dibenamine discussed effects enzyme epinephrine ester evidence free energy function guinea-pig hydrolysis hydrophobic interactions increased inhibition inhibitors ionic J-receptor kcal mole-1 ligand ligand binding lipid macromolecular mechanism membrane potential molecular molecules muscarinic N.Y. Acad Nature London neurotransmitter nonpolar norepinephrine permeability Pharmacol phospholipids Physiol polar Proc produce protein quaternary Rabbit relationship Reproduced with permission response role skeletal muscle smooth muscle solution specific spike structure studies substitution substrate subunit Table Ther tissue tubocurarine York