Medical Pharmacology and Therapeutics E-Book: Medical Pharmacology and Therapeutics E-BookMedical Pharmacology & Therapeutics provides all the information medical and healthcare students need throughout their degree programme and beyond, including for professional qualifications such as the PSA.This all-round textbook covers basic pharmacology through to drug prescribing in clinical contexts, covering the pathogenic mechanisms of disease; drug actions, side effects, and the therapeutic principles of drug use. It takes a helpful systems-based approach that orders information according to body systems and disease areas, rather than by drug class.Now in its sixth edition, the book has been fully updated to include latest scientific understanding of drug action and administration and current best practice in prescribing medications, informed by the latest national guidelines. - A clinical focus throughout – suitable for medical, nursing and other healthcare students throughout their training - Thorough update of clinically-relevant medicines to ensure best practice - Information aligned with the British National Formulary (BNF), NICE guidelines and relevant professional benchmarks - Comprehensive drug compendia allow all drugs to be identified and placed within their respective classes - Extensive self-assessment questions to support learning and revision - New to this edition Expanded discussion of the pathophysiology and management of shock - Revised discussion of the management of chronic pain - Consideration of treatment of Covid-19 |
Contents
| 1 | |
2 Pharmacokinetics | 32 |
3 Drug Discovery Safety and Efficacy | 62 |
4 Neurotransmission and the Peripheral Autonomic Nervous System | 71 |
5 Ischaemic Heart Disease | 89 |
6 Systemic and Pulmonary Hypertension | 108 |
7 Heart Failure and Shock | 128 |
8 Cardiac Arrhythmias | 142 |
31 Hyperuricaemia Gout and Pseudogout | 383 |
32 Nausea and Vomiting | 389 |
33 Dyspepsia Peptic Ulcer Disease and Gastrooesophageal Reflux Disease | 397 |
34 Inflammatory Bowel Disease | 408 |
35 Constipation Diarrhoea and Irritable Bowel Syndrome | 415 |
36 Liver Disease | 423 |
37 Obesity | 432 |
38 The Immune Response and Immunosuppressant Drugs | 437 |
9 Cerebrovascular Disease and Dementia | 160 |
10 Peripheral Artery Disease | 169 |
11 Haemostasis | 175 |
12 Asthma and Chronic Obstructive Pulmonary Disease | 192 |
Cough Respiratory Stimulants Cystic Fibrosis Idiopathic Pulmonary Fibrosis and Neonatal Re | 211 |
14 Diuretics | 218 |
15 Disorders of Micturition | 229 |
16 Erectile Dysfunction | 236 |
17 General Anaesthetics | 242 |
18 Local Anaesthetics | 252 |
19 Opioid Analgesics and the Management of Pain | 258 |
20 Anxiety ObsessiveCompulsive Disorder and Insomnia | 273 |
21 Schizophrenia and Bipolar Disorder | 281 |
22 Depression Attention Deficit Hyperactivity Disorder and Narcolepsy | 292 |
23 Seizures and Epilepsy | 308 |
24 Extrapyramidal Movement Disorders and Spasticity | 323 |
Multiple Sclerosis Motor Neuron Disease and GuillainBarré Syndrome | 336 |
26 Migraine and Other Headaches | 342 |
27 The Neuromuscular Junction and Neuromuscular Blockade | 350 |
28 Myasthenia Gravis | 357 |
29 Nonsteroidal Antiinflammatory Drugs | 361 |
30 Rheumatoid Arthritis Other Inflammatory Arthritides and Osteoarthritis | 371 |
39 Antihistamines and Allergic Disease | 450 |
40 Diabetes Mellitus | 457 |
41 The Thyroid and Control of Metabolic Rate | 473 |
42 Calcium Metabolism and Metabolic Bone Disease | 480 |
43 Pituitary and Hypothalamic Hormones | 491 |
44 Corticosteroids Glucocorticoids and Mineralocorticoids | 503 |
45 Female Reproduction | 512 |
46 Androgens Antiandrogens and Anabolic Steroids | 530 |
47 Anaemia and Haematopoietic ColonyStimulating Factors | 535 |
48 Lipid Disorders | 545 |
49 Skin Disorders | 558 |
50 The Eye | 567 |
51 Drugs for Infections | 578 |
52 Drugs for Cancer | 630 |
53 Drug Toxicity and Overdose | 661 |
54 Substance Abuse and Dependence | 677 |
55 Prescribing Adherence and Information About Medicines | 693 |
56 Drug Therapy in Special Situations | 700 |
| 712 | |
IBC | 745 |
Other editions - View all
Medical Pharmacology and Therapeutics Derek G. Waller,Anthony Sampson,Andrew Hitchings No preview available - 2021 |
Common terms and phrases
absorption ACE inhibitors acid activity acute adrenoceptor agonist anaesthesia anaesthetic analogue angiotensin ANSWERS antibacterial antibody antiinflammatory antipsychotic arterial asthma bacterial benzodiazepines binding block blockers blood Ca2+ cardiac cause cells channels Chapter cholesterol chronic clinical combination contraceptive coronary corticosteroid depolarisation diabetes mellitus diarrhoea disease disorders diuretics dopamine dose drug duration of action enzyme factors GABA gastric Given orally glucocorticoid glucose half-life headache heart failure hepatic histamine hormone hypertension increased infarction inflammatory infusion inhaled inhibitor inhibits injection insulin intracellular intramuscular intravenous ischaemic kidney levodopa liver Mechanism of action membrane metabolised metabolism metformin muscarinic myocardial myocardial infarction nausea neurons noradrenaline NSAIDs occur oestrogen opioid pain pathways peripheral Pharmacokinetics plasma concentration platelet prodrug produce progestogen protein receptor antagonist reduce release renal response risk seizures serotonin smooth muscle stimulation subcutaneous symptoms syndrome synthesis therapy tion tissue treat treatment ulcer unwanted effects usually vascular vasodilation ventricular vitamin vomiting warfarin