The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

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Bharat B. Aggarwal, Young-Joon Surh, S. Shishodia
Springer Science & Business Media, Aug 6, 2007 - Medical - 490 pages
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Curcumin is derived from the root of the plant Curcuma longa (also called turmeric) and its medicinal uses have been described for over 5000 years. More than 1500 papers published within last half a century has revealed that curcumin has a potential in the treatment of wide variety of inflammatory diseases including cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer, psoriasis etc, through modulation of numerous molecular targets. This is the first monograph to deal specifically with this subject.

 

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Contents

THE INDIAN SOLID GOLD
1
HIGHLY ACTIVE ANTICANCER CURCUMIN ANALOGUES
77
ANTIOXIDANT AND ANTIINFLAMMATORY PROPERTIES
105
MODULATION OF TRANSCRIPTION FACTORS BY CURCUMIN
127
CANCER CHEMOPREVENTIVE EFFECTS OF CURCUMIN
149
ANTITUMOR ANTIINVASION AND ANTIMETASTATIC
173
NEUROPROTECTIVE EFFECTS OF CURCUMIN
197
REGULATION OF COX AND LOX BY CURCUMIN
213
RADIOPROTECTION AND RADIOSENSITIZATION
301
IMMUNOMODULATIONBYCURCUMIN
321
BENEFICIAL ROLE OF CURCUMIN IN SKIN DISEASES Rajesh L Thangapazham Anuj Sharma and Radha K Maheshwari
343
CARDIOPROTECTIVE EFFECTS OF CURCUMIN Sumitra Miriyala Manikandan Panchatcharam and
359
PROTECTION FROM ACUTE AND CHRONIC LUNG DISEASES
379
NEPHROPROTECTIVE AND HEPATOPROTECTIVE EFFECTS
407
CURCUMIN AND AUTOIMMUNE DISEASE John J Bright
425
PHARMACOKINETICS AND PHARMACODYNAMICS
453

MOLECULAR TARGETS OF CURCUMIN
227
CELLGROWTHREGULATION
245
CURCUMINASCHEMOSENSITIZER
269
CLINICAL STUDIES WITH CURCUMIN
471
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