Advances in Behavioral Biology, Volume 34Plenum Press, 1971 - Biology |
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Page 56
... Scale bar = 100 μm . Figure 4 . The juxtanuclear inclusion of Pick disease , the Pick body , is recognized by antibodies to ubiquitin . In this light micro- graph , Pick bodies ( arrowheads ) are intensely immunostained by an affinity ...
... Scale bar = 100 μm . Figure 4 . The juxtanuclear inclusion of Pick disease , the Pick body , is recognized by antibodies to ubiquitin . In this light micro- graph , Pick bodies ( arrowheads ) are intensely immunostained by an affinity ...
Page 81
... ( bars ) ; 5 nm ( 1 ) and 10 nm ( 2 ) wide NFs ; continuity bet- ween NF and PHF - like strands ( arrowhead ) ; fine filament tangle ( T ) . Myelinated axon . Patient MBR . Scale bar = 0.1 um . Fig . 5 : P 5 The heterogeneous structure of.
... ( bars ) ; 5 nm ( 1 ) and 10 nm ( 2 ) wide NFs ; continuity bet- ween NF and PHF - like strands ( arrowhead ) ; fine filament tangle ( T ) . Myelinated axon . Patient MBR . Scale bar = 0.1 um . Fig . 5 : P 5 The heterogeneous structure of.
Page 93
... Scale bar = 0.1 μm . Figs . 13c , d : PHFS of a myelinated axon reminiscent of the double helical NF structure in Figs . 13a , b ; PHFs of barbed wire morphology ( 1 ) ; PHF fraying into protofilament components ( L ) ; protofilament ...
... Scale bar = 0.1 μm . Figs . 13c , d : PHFS of a myelinated axon reminiscent of the double helical NF structure in Figs . 13a , b ; PHFs of barbed wire morphology ( 1 ) ; PHF fraying into protofilament components ( L ) ; protofilament ...
Contents
A Review and Update | 1 |
The Phosphorylation of the Microtubuleassociated | 25 |
Human Amyloidosis and In Vitro Formation of Alzheimer Amyloid | 33 |
Copyright | |
16 other sections not shown
Common terms and phrases
Acad Sci USA Acta Neuropathol Berl actin actin filaments AD/SDAT alpha-actinin Alzheimer disease Alzheimer neurofibrillary tangles Alzheimer paired helical Alzheimer's disease amyloid fibrils amyloidosis antisera Autilio-Gambetti axonal transport bind Biochem Brain Res cDNA Cell Biol characterized contain cytoplasmic cytoskeletal electron microscopic epitopes et.al formation Gambetti Grundke-Iqbal hippocampus Hirano bodies Ihara Immunocytochemical studies immunoreactivity immunostained inclusions insoluble intermediate filaments Iqbal isolated Kosik KS Lewy bodies MAP2 MAPS micrographs microtubule assembly microtubule-associated protein molecular weight monoclonal antibodies Natl Acad Sci neurites neurofibrillary tangles neurofilament proteins neuronal cytoskeleton Neuropathol Exp Neurol Neurosci NF-H NF-L NF-M normal paired helical filaments Parkinson's disease Pathol perikarya Perry G PHF polypeptides phosphorylation Pick bodies Pick's disease plaque cores polyclonal Proc Natl Acad protofilaments Scale bar Selkoe DJ senile plaque sequence share antigenic determinants staining Sternberger structure subunit tau protein tropomyosin tubulin ubiquitin ultrastructural vinculin vitro Wisniewski Yen S-H