Combined Modality Cancer Therapy: Radiation and Infusional ChemotherapyJacob J. Lokich, John E. Byfield An innovative text presenting the experimental and clinical basis for combined modality cancer therapy. Special attention is given to employing infusional chemotherapy simultaneously with radiation. |
Contents
Interaction of Radiation with Specific Drugs | 4 |
Clinical Basis for Radiation and Infusional Chemotherapy | 15 |
Radiation Fractionation | 22 |
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5-fluorouracil 5-FU infusion 5-yr survival adenocarcinoma adjuvant administered anal canal anal cancer bladder bleomycin bolus Byfield Cancer Treat chemoradiation chemoradiotherapy cisplatin clinical trials combined modality therapy compared concomitant concurrent continuous infusion CR rate cycle cytotoxic disease disease-free drug effect esophageal cancer esophageal carcinoma evaluated external beam fractions given head and neck hepatic high-dose Hydroxyurea hypoxic cells I.A. infusion ifosfamide improved increased infused 5-FU infusional Int J Radiat interaction irradiation lesions liver locally advanced lung cancer malignant gliomas median survival metastases methotrexate mg/m² mg/m²/day misonidazole neck cancer Oncol Biol Phys patients received patients treated phase postoperative preoperative Radiat Oncol Biol radiation therapy radiosensitizers radiotherapy randomized study randomized trial recurrent regimen reported resection response rate soft tissue sarcomas split-course squamous cell carcinoma surgery surgical survival rate therapeutic total dose toxicity treatment tumor cells unresectable versus vitro