The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

Front Cover
Penguin, Aug 22, 2017 - Health & Fitness - 320 pages
The instant New York Times and Wall Street Journal bestseller

A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline.

Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease. 
In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline.  Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene.
The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer’s brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.

What people are saying - Write a review

User Review - Flag as inappropriate

Bookstores are full of self-help books that offer simple recipes for solving complex problems. It's easy for this book to be dismissed - chances are it's over-hyped. That would be a big mistake. Dr Bredesen really does have a cure for AD. The reason that it's been slow to gain recognition is the same reason that it works: It's complex, personalized, requiring a specially-trained doctor to do the diagnosis. It turns out there are at least 36 different causes that contribute to a single biochemical tipping point. To effectively treat AD, you need to know which of these causes are most important in your particular case, because it is impractical to address them all. Hence Dr Bredesen's protocol begins with an extensive battery of tests and an expert analysis, and proceeds to an individual prescription of life-style changes, diet, sleep, fasting, supplements, and prescriptions as a last step.
Dale Bredesen has a top-tier resume, with a background from the best of mainstream Western medicine. He has worked with the biochemistry in combination with the symptoms and test results of thousands of patients. What he has come up with is the opposite of the one-size-fits-all approach that we associate with mainstream medicine. This is the first example in medical history of a disease that has been conquered not with a single treatment, but with a comprehensive understanding of the full complexity of the body's systems, and a decision-tree for addressing many inputs to effect a single cure.
The book tells his history, with case studies of people who have come back from being unable to care for themselves to return to job and family. It also goes into details of test results and how to interpret them. You'll want to read the middle chapters with the perspective your doctor can provide. Get an extra copy for her.


Disrupting Dementia
From Bedside to Bench and Back
The God Gene and the ThreeTypes of Alzheimers Disease
Evaluation and Personalized Therapeutics
Reversing Cognitive Decline
Putting It All Together You Can Do
This Is Not EasyWorkarounds and Crutches
Machiavelli Meets Feynman

Other editions - View all

Common terms and phrases

About the author (2017)

Dale Bredesen, M.D., is internationally recognized as an expert in the mechanisms of neurodegenerative diseases such as Alzheimer’s disease. He graduated from Caltech, then earned his M.D. from Duke University Medical Center in Durham, North Carolina. He served as chief resident in neurology at the University of California, San Francisco (UCSF) before joining Nobel laureate Stanley Prusiner’s laboratory at UCSF as an NIH postdoctoral fellow. He held faculty positions at UCSF, UCLA, and the University of California, San Diego. Dr. Bredesen directed the Program on Aging at the Burnham Institute before coming to the Buck Institute in 1998 as its founding president and CEO. He is the chief medical officer of MPI Cognition.

Bibliographic information