Pharmacology in Exercise and SportsThis is the first book to describe the pharmacological interaction of drugs and exercise with organ systems at molecular and cellular levels. It explains the effect of exercise on pharmacokinetics and pharmacodynamics of drugs, and the activation or induction of antioxidant enzymes which may take place via the adenosine receptor or may occur due to gene expression. |
Contents
Introduction | 2 |
Chapter | 3 |
Effect of Exercise on Drug Distribution | 12 |
Effect of Exercise on Drug Metabolism | 18 |
Effect of Exercise on Renal Elimination | 28 |
Chapter 2 | 39 |
Exercise Drugs and Tissue Specific Antioxidant System | 57 |
Glutathione and Exercise | 97 |
Chapter 8 | 191 |
Chapter 9 | 211 |
Chapter 10 | 235 |
Chapter 11 | 263 |
Chapter 12 | 289 |
Chapter 13 | 317 |
Pharmacological Aspects of Yoga | 330 |
Future Perspectives | 341 |
Common terms and phrases
acetylcholine acetylcholinesterase acid acute exercise adenosine receptor agonist altered antioxidant enzyme activity Appl bed rest binding Biochem blood flow cardiac cardiovascular catecholamines cells choline choline acetyltransferase cholinergic chronic Circulation clearance Clin concentration cytosol decrease digoxin disease drugs due to exercise EDNO effect of exercise endurance training enhanced exercise training exercise-induced exhaustive exercise factors free radicals genes glucose glutathione GSH-Px GSSG heart heat shock hepatic hormone HSPs hypertension immune increase induced inhibition inhibitors interaction levels lipid peroxidation liver mechanisms mediated metabolism metabolites mitochondria myocardial nitric oxide nitric oxide synthase oxidative stress patients pharmacokinetics Pharmacol pharmacological physical activity physical exercise Physiol physiological physostigmine plasma platelet platelet activation propranolol protein reactive oxygen species reduced regulation release renal reported response to exercise role sedentary serum skeletal muscle Somani Sports Exerc studies superoxide synthase synthesis theophylline thromboxane tissue toxicity transcription treadmill vascular vasodilation yoga