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acetylcholine Acta Physiol action potential activity adrenergic adrenergic nerves afferent Anat arrow autonomic axons block Burnstock catecholamines Cell Biol cell bodies cholinergic cholinesterase chromaffin cells ciliary ganglion cleft cytoplasm deferens dendrites denervation dense-cored vesicles depolarization diameter discharge effect electron microscopic end plate excitation excitatory Exptl fast axoplasmic transport filaments fluorescent frog ganglion cells guinea pig histochemical hyperpolarization Iggo increase inhibitory innervation intrafusal Jacobowitz Katz and Miledi Koelle Koketsu Libet Lond mammalian nerve mechanism metabolism microtubules mitochondria muscle fiber myelin sheath nerve endings nerve fibers nerve terminals nervous system neurofilaments neuromuscular junction neurons Nishi observed Ochs Pacinian corpuscles Pharmacol physiological plexus postganglionic postsynaptic preganglionic fibers presynaptic Proc profiles protein rabbit receptors region release response Schwann cells sciatic nerve smooth muscle spindle stimulation structure studies superior cervical ganglion sympathetic ganglia synaptic vesicles threshold tissue transmission transmitter ultrastructure varicosities vitro voltage