Smart Polymers for Bioseparation and BioprocessingSmart polymers are macromolecules capable of undergoing rapid, reversible phase transitions from a hydrophilic to a hydrophobic microstructure when triggered by small changes in their immediate environment, such as slight variations in temperature, pH or ionic strength. Until now, it has always been considered that polymers are passive participants within the Bioseparation procedure. Smart Polymers for Bioseparation and Bioprocessing addresses an entirely novel theory that advocates a much more active role for smart polymers within this process than has previously been envisaged, and therefore focuses on the role of these smart polymers within bioseparation. With contributions from the leading researchers working on smart polymers and their applications, this volume offers a comprehensive overview of both the current state-of-affairs within this research field and the potential for future developments. This book will be of interest to those working on techniques of bioseparation and bioprocessing, polymer chemists developing new smart polymers, as well as graduates in biotechnology. |
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Contents
1 Temperature and pHsensitive graft Copolymers | 1 |
2 Synthesis of novel smart polymers for bioseparation and bioprocessing | 33 |
3 Affinity precipitation of proteins using smart polymers | 68 |
4 Aqueous twophase systems with smart polymers | 96 |
5 Polycomplexes for bioseparation and bioprocessing | 121 |
6 Controlled permeation through membranes modified with smart polymers | 151 |
7 Applications of smart hydrogels in separation | 174 |
8 Surfaces coated with smart polymers | 203 |
9 Smart latexes for bioseparation and bioprocessing | 238 |
10 Application of water soluble polymers and their complexes | 259 |
11 Enzymes immobilized in smart hydrogels | 287 |
12 Stimuli responsive polymers in bioprocessing | 322 |
355 | |
Other editions - View all
Smart Polymers for Bioseparation and Bioprocessing Igor Galaev,Bo Mattiasson No preview available - 2001 |
Common terms and phrases
acid activity added addition adsorbed adsorption affinity precipitation amount antibodies applications aqueous aqueous solution aqueous two-phase assay behavior binding buffer carrier cells chains changes charged Chem Chen chromatography compared complexes composition concentration conjugate containing critical crosslinked cycling decrease dependence developed drug effect et al ethanol extract Figure formation formed function glucose graft copolymers groups higher Hoffman hydrogels hydrophobic immobilized enzyme immunoassay increase initiator insoluble interaction ionic Izumrudov latex layer LCST ligand lower Mattiasson membrane method microcapsules microspheres mixture molecules monomer NIPAAm observed obtained particles partitioning pervaporation phase transition Pluronic PNIPAM poly polyelectrolyte polyions polymer polymerization prepared present properties protein purification ratio reaction relatively release respectively response salt separation shown shows soluble solution solvent specific starch structure studied substrate surface swelling Synthesis temperature thermosensitive two-phase systems viscosity volume water-soluble