Smart Polymers for Bioseparation and Bioprocessing
Igor Galaev, Bo Mattiasson
CRC Press, Nov 15, 2001 - Technology & Engineering - 304 pages
Smart polymers are macromolecules capable of undergoing rapid, reversible phase transitions from a hydrophilic to a hydrophobic microstructure when triggered by small changes in their immediate environment, such as slight variations in temperature, pH or ionic strength. Until now, it has always been considered that polymers are passive participants within the Bioseparation procedure. Smart Polymers for Bioseparation and Bioprocessing addresses an entirely novel theory that advocates a much more active role for smart polymers within this process than has previously been envisaged, and therefore focuses on the role of these smart polymers within bioseparation.
With contributions from the leading researchers working on smart polymers and their applications, this volume offers a comprehensive overview of both the current state-of-affairs within this research field and the potential for future developments. This book will be of interest to those working on techniques of bioseparation and bioprocessing, polymer chemists developing new smart polymers, as well as graduates in biotechnology.
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1 Temperature and pHsensitive graft Copolymers
2 Synthesis of novel smart polymers for bioseparation and bioprocessing
3 Affinity precipitation of proteins using smart polymers
4 Aqueous twophase systems with smart polymers
5 Polycomplexes for bioseparation and bioprocessing
6 Controlled permeation through membranes modified with smart polymers
7 Applications of smart hydrogels in separation
Other editions - View all
acid acrylamide activity adsorbed adsorption affinity precipitation AIBN amino antibodies antigen aqueous solution aqueous two-phase systems assay binding bioprocessing bioseparation Biotechnol buffer carrier cells chains changes charged Chem Chen chromatography cloud point composition concentration conjugate critical solution temperature crosslinked cycle D-AS decrease dextran enzyme enzyme immobilization ethanol Eudragit Galaev graft copolymers groups Hoffman hydrogels hydrolysis hydrophilic hydrophobic immobilized enzyme immunoassay increase insoluble interaction interpolyelectrolyte reactions ionic strength Izumrudov Johansson Kabanov Kokufuta latex particles layer LCST ligand Macromolecules macromonomer Mattiasson membrane methacrylate microcapsules microspheres mixture molecular weight molecules monomer N-isopropylacrylamide NaCl NIPAAm NPEC NVIBA PAAc partitioning PEVP phase transition Pluronic PNIPAM poly poly(NIPAAm poly(NVIBA polyanion polycation polyelectrolyte polyelectrolyte complexes polyions polymer polymerization polystyrene prepared properties purification random copolymers ratio raw starch reactor salt smart polymers soluble solvent substrate surface swelling Synthesis temperature-sensitive thermo-responsive thermolysin thermoseparating Tjerneld TR adsorbent trypsin viscosity water-soluble Zezin