Smart Polymers for Bioseparation and Bioprocessing

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Igor Galaev, Bo Mattiasson
CRC Press, Nov 15, 2001 - Technology & Engineering - 304 pages
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Smart polymers are macromolecules capable of undergoing rapid, reversible phase transitions from a hydrophilic to a hydrophobic microstructure when triggered by small changes in their immediate environment, such as slight variations in temperature, pH or ionic strength. Until now, it has always been considered that polymers are passive participants within the Bioseparation procedure. Smart Polymers for Bioseparation and Bioprocessing addresses an entirely novel theory that advocates a much more active role for smart polymers within this process than has previously been envisaged, and therefore focuses on the role of these smart polymers within bioseparation.
With contributions from the leading researchers working on smart polymers and their applications, this volume offers a comprehensive overview of both the current state-of-affairs within this research field and the potential for future developments. This book will be of interest to those working on techniques of bioseparation and bioprocessing, polymer chemists developing new smart polymers, as well as graduates in biotechnology.
 

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Contents

1 Temperature and pHsensitive graft Copolymers
1
2 Synthesis of novel smart polymers for bioseparation and bioprocessing
33
3 Affinity precipitation of proteins using smart polymers
68
4 Aqueous twophase systems with smart polymers
96
5 Polycomplexes for bioseparation and bioprocessing
121
6 Controlled permeation through membranes modified with smart polymers
151
7 Applications of smart hydrogels in separation
174
8 Surfaces coated with smart polymers
203
9 Smart latexes for bioseparation and bioprocessing
238
10 Application of water soluble polymers and their complexes
259
11 Enzymes immobilized in smart hydrogels
287
12 Stimuli responsive polymers in bioprocessing
322
Index
355

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