Inferring Modern Human Migration Patterns Within Africa Using Calibrated Mitochondrial and Y-chromosomal DNA.

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ProQuest, 2009 - 140 pages
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The aim of this thesis is to characterize African population genetic structure, with a focus on eastern and southern Africa, and relate the inferred population history to linguistic patterns and the archaeological record. The substructure of African populations has major implications for hypotheses regarding behaviorally modern human origins. If behavioral modernity was caused by a relatively small number of genetic mutations as has been proposed, then knowledge of African population substructure constrains the timing and process of a selective sweep. Using a diverse set of populations from eastern Africa, I show that mitochondrial and Y-chromosomal data support a model of ancient divergence between African click-speaking populations with little recent gene flow. Evidence of recent gene flow between eastern and southern Africa is constrained to a migration of pastoralists about 2,000 years ago through Tanzania to the northern fringe of southern Africa.

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History of ClickSpeaking Populations of Africa Inferred from
Ychromosomal Evidence of a Pastoralist Migration through
Rapid Global Demographic Expansions After the Origins of

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