Alcohol, Drugs of Abuse, and Immune Functions

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Ronald R. Watson
CRC Press, May 4, 1995 - Medical - 288 pages
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Substance abusers are an immunocompromised population, vulnerable to a wide array of new and resurgent infectious diseases - in spite of modern treatment. For example, opportunistic infections like tuberculosis are the principal cause of morbidity and mortality in HIV positive patients. Alcohol- and drug-induced disorders are wide-ranging, gaining prominence as the spectrum of emerging diseases broadens.

Alcohol, Drugs of Abuse, and Immune Functions reviews the role of these immunosuppressants as cofactors in disease. It covers the basic biology and immunology of impairments to defense against infectious disease. Alcohol and drug use is consistently associated with immunosuppression, although it isn't known if it is the substance itself, a metabolite, or an indirect effect that alters disease resistance. This text explores the advances toward answering this question, examines alcohol in different settings, its relationship to important cells, and the effects it can have on vital organs such as the liver and the lungs.
 

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Contents

Chapter
2
Chapter
10
Conclusions
11
The Effect of Alcohol on the Cellular Immune Function
17
Ardestani and Watson
42
T Cell Modulations in Human Alcoholics
57
Chapter 6
87
Chapter 7
105
Do Alcohol and Other Substances of Abuse Alter
165
Chapter 12
185
Dysregulation in Cytokine Production by Alcohol
201
Chapter 15
215
The Role of Alcohol in EndocrineImmune Interactions
229
Chapter 16
245
Index
259
Copyright

Chapter 8
121

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About the author (1995)

Ronald Ross Watson, Ph.D., is an internationally recognized nutritionist and immunologist who has studied the importance of nutrients on anti-cancer immune defense for twenty years. He has edited 52 biomedical books and directs four NIH funded biomedical grants.

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