Guide for Laboratory Animal Facilities and Care

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U.S. Department of Health, Education, and Welfare, Public Health Service, 1965 - Laboratory animals - 45 pages

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Page 3 - ... and reasonably expected to be present in such feed or water are not present at levels above those specified in the protocol. Documentation of such analyses shall be maintained as raw data. (h) Bedding used in animal cages or pens shall not interfere with the purpose or conduct of the study and shall be changed as often as necessary to keep the animals dry and clean.
Page 20 - ... activities from animal rooms to areas specifically designed for this purpose. The use of sound-reducing materials in animal rooms can be helpful. Concrete walls are more effective than metal or plaster walls in containing sound because density is more important than acoustical materials in reducing the transmission of sound. Acoustical materials may be used in animal rooms by direct application to the ceiling, or as part of a suspended ceiling, providing the rooms are vermin-proof. The elimination...
Page 16 - Ceilings Ceilings formed by the concrete floor above are satisfactory if properly smoothed, sealed, and painted. Furred ceilings of plaster or fire code plasterboard should be sealed and painted with a washable finish. Exposed pipes and fixtures at ceiling level are undesirable, especially in nonhuman primate rooms, because of the problems created by escaped animals.
Page 4 - Vermin control programs should be instituted in new buildings prior to occupancy. Effective control and ultimate elimination can be attained in older buildings, even where heavy infestation has occurred. This can be accomplished by sealing or eliminating all breeding sites, and by using pesticides or trapping procedures in conjunction with a strict program of sanitary maintenance. Pesticide application must be carried out under professional supervision in order to avoid toxic effects on the animals...
Page 19 - ... turnover. Bulk supplies of food and bedding should not be stored in animal rooms. A separate area or room should be available in which food and bedding can be stored off the floor on pallets, racks, or carts. A continuing pest control program is essential. It is most desirable for the storage areas to be vermin-proof. Food storage areas should be physically separated from refuse areas. Temperatures in the storage rooms may be the ambient temperature. However, it is good practice to hold packaged...
Page 16 - If windows are provided, it is preferable that they be nonopening, without sills or horizontal surfaces where dust can collect, of an insulating construction (in areas of temperature extremes) , and sealed with a material that will withstand repeated washing and disinfecting. If windows are opened for ventilation purposes, effective screening is essential. 4. Floors Floors should be smooth, waterproof, nonabsorbent, nonslip, wear resistant, acid and solvent resistant, capable of being scrubbed with...
Page 11 - Among these are the type of institution ; its size ; the nature of the administrative structure for animal care; the nature of the physical plant; the number and species of the animals maintained ; and the nature of the teaching, testing, or research activities. It is evident that these interactions will result in a variety of staffing concepts and "chains of command," and, therefore, no arbitrary statement can be made concerning personnel requirements.

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