The Physical Basis of Biochemistry: The Foundations of Molecular Biophysics

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Springer Science & Business Media, Sep 10, 2010 - Science - 949 pages
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Biological chemistry has changed since the completion of the human genome project. There is a renewed interest and market for individuals trained in biophysical chemistry and molecular biophysics. The Physical Basis of Biochemistry, Second Edition, emphasizes the interdisciplinary nature of biophysical chemistry by incorporating the quantitative perspective of the physical sciences without sacrificing the complexity and diversity of the biological systems, applies physical and chemical principles to the understanding of the biology of cells and explores the explosive developments in the area of genomics, and in turn, proteomics, bioinformatics, and computational and visualization technologies that have occurred in the past seven years. The book features problem sets and examples, clear illustrations, and extensive appendixes that provide additional information on related topics in mathematics, physics and chemistry.
 

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Contents

Part II Foundations
107
Part III Building a Model of Biomolecular Structure
388
Part IV Function and Action Biological State Space
604
Part V Methods for the Measuring Structure and Function
738
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About the author (2010)

Kevin Hallock, Ph.D., is a researcher and instructor in the Department of Anatomy and Neurobiology at the Boston University School of Medicine in Boston, Masschusetts, where he teaches biostatistics, an graduate course on the science of disasters, and co-teaches biophysical chemistry and modeling courses with Dr. Bergethon. His research interests include the impact of antimicrobial peptide on phospholipid bilayers, solid-state NMR and magnetic resonance imaging characterization of crystalline solids, atherosclerotic plaque formation, magnetic resonance microscopy of arthropods, the impact of chronic Hg exposure on aging, and the role cell membrane biophysics play in the fundamental processes of neurophysics. Peter Bergethon, MD is the Head of the Neuroscience Interdisciplinary Modeling and Simulation Center (NIMS Center), the Laboratory for Intelligence Modeling and Neurophysics and a member of the faculty in both the Departments of Anatomy/Neurobiology and Biochemistry at Boston University School of Medicine. His research spirals around a core question: "What is the physical and systemic basis for creativity and intelligent behavior and how could such behavior be practically constructed or reconstructed?" Dr. Bergethon is also an active member of the American Academy of Neurology from which he received the Founder's Award, the Electrochemical, Biophysical, American Chemical Societies, the Society for Neuroscience and the American Society of Biochemistry and Cellular Biology.

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