The Neuron: Cell and Molecular Biology
The third edition of The Neuron provides a comprehensive first course in the cell and molecular biology of nerve cells. The first part of the book covers the properties of the many ion channels that shape the way a single neuron generates varied patterns of electrical activity, as well as the molecular mechanisms that convert electrical activity into the secretion of neurotransmitter hormones at synaptic junctions between neurons. The second part covers the biochemical pathways that are linked to the action of neurotransmitters and can alter the cellular properties of neurons or sensory cells that transduce information from the outside world into the electrical code used by neurons. The final section reviews our rapidly expanding knowledge of the molecular factors that induce an undifferentiated cell to become a neuron, and then guide it to form appropriate synaptic connections with its partners. This section also focuses on the role of ongoing experience and activity in shaping these connections, and finishes with an account of mechanisms thought to underlie the phenomena of learning and memory.
What people are saying - Write a review
We haven't found any reviews in the usual places.
Signaling in the Brain
Form and Function in Cells of the Brain
Electrical Properties of Neurons
Electrical Signaling in Neurons
Membrane Ion Channels and Ion Currents
Ion Channels Are Membrane Proteins
Ion Channels Membrane Ion Currents and the Action Potential
Receptors and Transduction Mechanisms II Indirectly Coupled ReceptorIon Channel Systems
Neuromodulation Mechanisms of Induced Changes in the Electrical Behavior of Nerve Cells
Behavior and Plasticity
The Birth and Death of a Neuron
Neuronal Growth and Trophic Factors
Adhesion Molecules and Axon Pathfinding
Formation Maintenance and Plasticity of Chemical Synapses
Diversity in the Structure and Function of Ion Channels
How Neurons Communicate Gap Junctions and Neurosecretion
Synaptic Release of Neurotransmitters
Neurotransmitters and Neurohormones
Receptors and Transduction Mechanisms I Receptors Coupled Directly to Ion Channels
Other editions - View all
acetylcholine receptor action potential amino acids axons behavior binding brain brane calcium channels cDNA cell bodies cellular chan changes channel protein Chapter chemical cloning complex components cyclic AMP cytoplasmic dendrites depolarization domain electrical activity electrical synapses encoding enzyme ephrins example exocytosis extracellular Figure function G protein ganglion genes glutamate gradient growth cone growth factor hair cells hormones hyperpolarization inactivation injection inputs interactions ion channels ligand long-term mechanisms membrane potential messenger RNA modulation molecular molecules motor neurons muscle mutations nerve nervous system neural neurite neuromuscular junction neurotransmitter neurotrophins nicotinic NMDA normal occurs olfactory pathway pattern peptide phosphorylation plasma membrane pore potassium channels potassium current properties protein kinase region response retina role second messenger sensory neurons sequence serotonin Shaker signaling sodium channels specific spinal cord stimulation structure subunits synaptic vesicles synthesis target tectum tein termed tion transduction transmitter release transport tyrosine voltage-dependent
Page 581 - K. Palczewski, T. Kumasaka, T. Hori, CA Behnke, H. Motoshima, BA Fox, I.
Page 578 - C. Methfessel, M. Mishina, T. Takahashi, T. Takai, M. Kurasaki, K. Fukuda, and S. Numa. (1985) Role of acetylcholine receptor subunits in gating of the channel.
Page 584 - Serafini, T., Kennedy, TE, Galko, MJ, Mirzayan, C., Jessell, TM, and Tessier-Lavigne, M. (1994). The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.
Page 575 - JE (1997). Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy. Cell 90, 523-535.
Page 573 - Jan LY (1988) Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila. Nature...