Part I. Elucidation of the Course of the Characteristic Ring D Fragmentation of Unsaturated Steroids: Part II. Characteristic Fragmentations of Cholesterol and Cholesterol Acetate |
From inside the book
Results 1-3 of 16
Page 68
... deuterium labeling results ( Tables I and II ) de- monstrate that carbons 7 , 9 , 11 and 14 are included in this ... deuterium transfer of the labeled cholesten - 3a - ol methyl ethers ( m / e 245 ) with the corresponding cholestenes ( m ...
... deuterium labeling results ( Tables I and II ) de- monstrate that carbons 7 , 9 , 11 and 14 are included in this ... deuterium transfer of the labeled cholesten - 3a - ol methyl ethers ( m / e 245 ) with the corresponding cholestenes ( m ...
Page 125
... labeled with deuterium allowing analysis of the origin of the methyl group lost from the molecular ion . The extensive use of remote functionalization techniques provided access to deuterium labeling at carbons 7 9 , 11 , 12 , 14 , 18 ...
... labeled with deuterium allowing analysis of the origin of the methyl group lost from the molecular ion . The extensive use of remote functionalization techniques provided access to deuterium labeling at carbons 7 9 , 11 , 12 , 14 , 18 ...
Page 130
... deuterium labels . The utility of isotopic labeling studies is perhaps most graphically illustrated by the only recently achieved unambiguous determination of the origin of the characteristic fragments in the mass spectrum of ...
... deuterium labels . The utility of isotopic labeling studies is perhaps most graphically illustrated by the only recently achieved unambiguous determination of the origin of the characteristic fragments in the mass spectrum of ...
Common terms and phrases
7-steroids 70 ev Fig 70eV Spectrum 80 Relative Abundance Abundance 40 20 acetic acid acetone allylic Anal analogous angular methyl group benzoate brine and dried C-3 equatorial calc Cent Total lonization Chem Cholest-8 cholestenes cholesterol acetate chromatography deuterium labeling deuterium transfer diglyme Djerassi double bond dried over MgSO4 eluted ether/hexane evaporated extracted into ether free sterol hydrogen transfer ionized isomerization isotopic composition ketone labeled cholesterols lead tetraacetate loss of C-19 m/e Per Cent Mass Spectral Peaks mass spectrometer mass spectrum metastable defocusing methanol mixture NMR identical olefins oxidation peak at m/e pregnane proton R₁ R₂ radical recrystallized recrystallized from methanol reduced refluxed Relative Abundance 40 result ring D cleavage ring D fragment rinsed saturated steroids Scheme side chain silica solvent spectra Spectrum of 5a-Cholest-8 spectrum of cholesterol steroidal olefins steroids sterol stirred substituent Table Total lonization 40 unlabeled compound vinyl