Click Reactions in Organic Synthesis
John Wiley & Sons, Sep 13, 2016 - Science - 360 pages
This book on click reactions to focus on organic synthesis, this reference work describes the click concept and underlying mechanisms as well as the main applications in various fields. As such, the chapters cover green chemical synthesis, metal-free click reactions, synthesis of pharmaceuticals, peptides, carbohydrates, DNA, macrocycles, dendrimers, polymers, and supramolecular architectures.
By filling a gap in the market, this is the ultimate reference for synthetic chemists in academia and industry aiming for a fast and simple design and synthesis of novel compounds with useful properties.
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Other editions - View all
1,3-dipolar cycloaddition 1,4-disubstituted acid activity alkyl amide bond amine analogs Angew anions aryl aryl azides ATRP azide and alkyne azide–alkyne cycloaddition benzyl Bioconjugate catalyst catalyzed cell chain end Chem Chen click chemistry click reaction CO2Et complex compounds conjugated COOH copolymer copper(I coworkers cross-linked Cu(I CuAAC reaction CuSO4 cyclic polymers cycloaddition reaction dendrimers derivatives developed DMSO drug efficient equiv ester Figure Fokin formation functional groups glycoconjugates Green Chem high yields Huisgen inhibitors intermediate ketones Lett ligands linear macrocycles Macromolecules Meldal moiety molecular molecules monomer nanoparticles nucleophilic nucleoside OH OH one-pot Pasini peptides polymerization polymers potential prepared propargyl protein react reactive regioselective room temperature Scheme Sharpless sodium azide solvents strategy structures substituted substrates synthesis terminal alkynes Tetrahedron thiol-based click thiol–ene thiols triazole triazole-linked triazolyl utilized Wang Zhang