Click Reactions in Organic Synthesis

Front Cover
Srinivasan Chandrasekaran
John Wiley & Sons, Sep 13, 2016 - Science - 360 pages
This book on click reactions to focus on organic synthesis, this reference work describes the click concept and underlying mechanisms as well as the main applications in various fields. As such, the chapters cover green chemical synthesis, metal-free click reactions, synthesis of pharmaceuticals, peptides, carbohydrates, DNA, macrocycles, dendrimers, polymers, and supramolecular architectures.
By filling a gap in the market, this is the ultimate reference for synthetic chemists in academia and industry aiming for a fast and simple design and synthesis of novel compounds with useful properties.
 

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Contents

Applications of Click Chemistry in Drug Discovery
25
Green Chemical Synthesis and Click Reactions
77
Synthesis of Substituted 123Triazoles through Organocatalysis
99
Applications of the CuCatalyzed AzideAlkyne Cycloaddition CuAAC
141
Synthesis of Diverse CarbohydrateBased Molecules using Click
161
AzideAlkyne Click Reaction in Polymer Science
203
Reactions
249
ThiolBased Click Chemistry for Macromolecular Architecture
255
Synthesis of Macrocycles and Click Chemistry
287
Modifications of Nucleosides Nucleotides and Nucleic Acids using
309
3
316
Index
337
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About the author (2016)

Srinivasan Chandrasekaran is an Honorary Professor and SERB Distinguished Fellow at the Department of Organic Chemistry, Indian Institute of Science, Bangalore, India. He received his M.Sc. and Ph.D. from the University of Madras, India, in 1967 and 1972, respectively. He was a research associate at Harvard University (USA) with Prof. E.J. Corey, and Syntex Research (Palo Alto, USA). He has published over 250 research papers in national and international journals and served as an elected member of the Bureau of IUPAC and Member of the Executive Committee of IUPAC. He is the Chairman of the National Organic Symposium Trust (NOST), India and was the President of the Chemical Research Society of India (CRSI) from 2012 to 2014. He was the editor-in-chief of Tetrahedron Letters published by Elsevier( 2007-14) and is currently on the Board of Consulting Editors. His major research interests lie in the areas of development of new synthetic methodologies and organometallic chemistry, total synthesis of natural products, homogeneous and heterogeneous catalysis, and organic materials.

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