Myocardial Preservation, Preconditioning, and AdaptationDipak Kumar Das, Richard M. Engelman, K. M. Cherian (M.D.) In this volume, basic scientists, cardiologists and cardiac surgeons discuss all that is known about preconditioning/adaptation and how this state-of-the-art technique compares with conventional techniques of myocardial preservation, unveiling its mechanism of protection and potential clinical application. |
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Contents
The Slowing of Ischemic Energy Demand in Preconditioned Myocardium | 13 |
Cardioprotection by Ischemic and Nonischemic Myocardial Stress | 27 |
Contribution to the Factors Involved in the Protective Effect of Ischemic | 43 |
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acid activity adaptation adenosine receptor agonists amiloride anoxia antioxidant aortic arrhythmias ATPase baseline Biochem Biol bradykinin buffer bypass Ca2+ calcium cardiac Cardiol cardiomyocytes cardioplegia cardioprotection Cardiovasc catalase cells cellular Circ Circulation contractile function control hearts coronary artery occlusion cytosolic D. M. YELLON decreased endogenous enzyme FIGURE free radicals gene expression global ischemia glutathione glycogen heat shock protein heat stress HSP 70i hypertrophied increased induced inhibition inhibitor injury inotropic intracellular ischemia and reperfusion ischemia/reperfusion ischemic preconditioning isoforms isolated rat heart isoproterenol J. M. DOWNEY left ventricular levels lipid MARBER mechanism mediated membrane metabolic minutes mitochondrial mRNA muscle myocardial infarction myocardial protection myocytes myosin normothermic oxidative stress oxygen patients perfused period of ischemia peroxide Pharmacol phospholipase phosphorylation Physiol postischemic preischemic pretreatment protein kinase rabbit heart reduced role sarcolemmal significantly stimulation stress protein stunning surgery tion tissue transgenic translocation xanthine