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Model of unidirectional gene conversion
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adenine amino acid amino acid sequence band binding bottom strand bp sequence cleaved cognate sequence contacts containing cytoplasmic deletion analysis detected dimer DNA cleavage DNA sequences EcoRI EcoRV EDTA electrophoresed encoded Endo.SceI eucaryotes exon exon sequences expression of l-Ppol extracts fraction gel filtration gel mobility shift gene genomic group I introns guanines homing endonucleases I-PpoI I-SceII immunoblotting incubated indicated indirect readout interaction intron intron homing intron insertion point intron sequences intron-encoded endonucleases kink l-Ppol l-Ppol activity l-Ppol ORF l-Scel l-Tevl LAGLI-DADG lanes methylation Mg2+ minor groove mobile intron mobility shift assays molecular weight molecule MPE*Fe(II mRNA mutagenesis mutants Northern blot nuclear nucleotides nucleus ORF RNA phage Physarum plasmid Ppol protection protein protein-DNA complex rDNA recognition sequence restriction enzymes ribozyme secondary structure sedimentation self-splicing sequencing ladder sequencing products specific splicing target Tris-HCl pH Tt LSU upstream exon vitro vivo wild type yeast