Traumatic Brain and Spinal Cord Injury: Challenges and DevelopmentsCristina Morganti-Kossmann, Ramesh Raghupathi, Andrew Maas Traumatic Brain and Spinal Cord Injury comprehensively covers the medical and pathological issues related to neurotrauma and its often devastating consequences. Written by globally renowned experts in the field, both clinicians and researchers will find this book invaluable to update their knowledge. This volume is divided into two sections, one covering the brain, the other the spinal cord. Each section discusses the following topics: • The demographic in the developed and developing world where neurotrauma is witnessing a massive expansion • Major clinical issues including advanced semi-experimental monitoring techniques utilized by neurosurgeons and intensivists and the potential use of identifying markers of tissue injury • Overview of major pathophysiological changes • The development of animal models; successes and limitations • Past, current and future therapeutic strategies including rehabilitative opportunities. Presenting the most up-to-date clinical and experimental research in neurotrauma, this volume is essential reading for neurologists, neurosurgeons, intensive care physicians and rehabilitative physicians. |
Contents
17 | 2 |
Gourikumar K Prusty Republic | 17 |
Benglis Jr Spinal Cord Injury Center University Hospital | 82 |
Current evaluation of TBI brain injury | 103 |
with improved preventive measures 1 Ronald L Hayes | 114 |
what | 126 |
Psychological effects of mild Ramesh Raghup athi and Jimmy W | 138 |
Developments of neuroimaging Cerebral inflammation after traumatic | 155 |
Ricky Rasschaert Brett Trimble | 194 |
Traumatic Spinal Injury | 216 |
Classification and surgical | 229 |
pathophysiology | 242 |
Modeling the injured spinal cord | 252 |
Myelin inhibitors of neurite | 264 |
Controversies on the role | 272 |
Hospital Adelaide Australia Australia Australia | 280 |
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activity acute adult animal models assessment associated astrocytes benefit biomarker blast injury Brain Res calpain cells cerebral clinical trials cognitive controlled contusion cortex cortical cytokines damage death decreased deficits defined detection diffuse diffuse axonal injury diffuse brain injury diffusion tensor imaging edema effects experimental factors findings first fluid focal following TBI following traumatic brain function glucose glutamate head injury helmet hippocampus human hypothermia imaging impact impaired improved increased INeurotrauma inflammatory influence intracranial lesions levels locomotor macrophages measures mechanisms metabolism microdialysis microglia mild TBI mild traumatic brain monitoring Morganti-Kossmann mortality motor mTBI myelin neurofilament neurological neuronal Neurosci Neurosurg NMDAR outcome oxygen pediatric plasticity post-injury post-traumatic potential protein PTSD receptor recovery reduce reported secondary severe TBI severe traumatic brain significant significantly specific spinal cord injury spine symptoms TBI patients therapeutic therapy tion tissue traffic traumatic brain injury treatment white matter