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absence of PMA adherent cells anaphylatoxin antibody antigen APRs assay astrocytes augment bioassays brain C3H/HeJ thymocytes cell biology cellular Characterization cloned cytolytic ConA concentrations contain CRP and SAP CT6 cells CTLL-20 cells culture supernatants cytokines detected EL4 supernatant endogenous estradiol estradiol and progesterone fibroblast fraction function glioblastoma cells growth factors helper activity hepatocytes human C5a HYBRIDOMA IL-1 activity IL-1 production IL-1-like factors IL-2-dependent cell line Immunol Immunology incubation induce inflammatory inhibit INTERFERON Interleukin-1 kilodaltons lectin lectin-activated thymocytes lymphocytes lymphokine preparation macrophages Mary Ann Liebert mediated mice mitogenic lymphokines MIZEL MLC cells MLC SN Molecular monoclonal monokine MORTENSEN mouse SAP murine nonspecific Number observed OPPENHEIM Orosz phagocytic phagocytosis placental monocytes producing IL-1 progesterone protein release ROOPENIAN SAP response SAP-inducing activity serum specific splenocytes steroids stimulation of IL-1 supernatant fluids supernatants suppressor factor synthesis T-cell T-lymphocyte tg/ml thymocyte proliferation thymocytes tion tissue culture tumor vitro Volume