Advances in Enzymology and Related Areas of Molecular Biology, Volume 78
Eric J. Toone
John Wiley & Sons, Oct 13, 2011 - Science - 500 pages
This book covers important advances in enzymology, explaining the behavior of enzymes and how they can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes. Advances in Enzymology focuses on enzymes, the primary catalysts of life processes. The explanation of the behavior of enzymes can be found via studies of their chemical mechanisms and can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes. The transglutaminases, first described in 1957, are a large, widely-distributed family of enzymes canonically responsible for the amidation/transamidation of protein side chains. The extraordinary diversity of names associated with various enzymatic activities now recognized and aggregated as transglutaminase bears witness to the remarkable diversity of biological roles associated with the activity, including myriad human diseases.
What people are saying - Write a review
We haven't found any reviews in the usual places.
AND RELATED AREAS OF MOLECULAR BIOLOGY Physiopathological Roles of Human Transglutaminase 2
AND RELATED AREAS OF MOLECULAR BIOLOGY Transglutaminase in Epidermis and Neurological Disease or What Makes a Good CrossLinki...
AND RELATED AREAS OF MOLECULAR BIOLOGY Transglutaminase 2 A New Paradigm for NF B Involvement in Disease
AND RELATED AREAS OF MOLECULAR BIOLOGY Transglutaminase 2 At the Crossroads between Cell Death and Survival
AND RELATED AREAS OF MOLECULAR BIOLOGY Tissue Transglutaminase and Its Role in Human Cancer Progression
AND RELATED AREAS OF MOLECULAR BIOLOGY Transglutaminase 2 Dysfunctions in the Development of Autoimmune Disorders Celiac Dise...
AND RELATED AREAS OF MOLECULAR BIOLOGY Effects and Analysis of Transglutamination on Protein Aggregation and Clearance in Neuro...
AND RELATED AREAS OF MOLECULAR BIOLOGY TransglutaminaseMediated Remodeling of the Human Erythrocyte Membrane Skeleton Rele...
AND RELATED AREAS OF MOLECULAR BIOLOGY Irreversible Inhibitors of Tissue Transglutaminase
AND RELATED AREAS OF MOLECULAR BIOLOGY Methionine Adenosyltransferase SAdenosylmethionine Synthetase
AND RELATED AREAS OF MOLECULAR BIOLOGY Color Plate
Acad AdoMet aggregates Alzheimer’s disease amine amino acid antibodies apoptosis apoptotic apoptotic cells autoimmune autophagy binding Biochem Biophys brain Ca2+ cancer cells catalytic celiac disease Cell Biol cell death cellular Chem complex cross-linking cystamine cysteine deamidation differentiation dimer domain effects enzyme erythrocytes extracellular factor factor XIII Fesus fibronectin formation function gene gliadin gliadin peptides glutamine gluten human huntingtin Huntington’s disease identified Immunol increased induced inflammatory inhibition inhibitors integrin interaction involucrin involved keratinocytes kinase Lewy bodies liver Lorand lysine macrophages matrix mechanism Melino membrane methionine methionine adenosyltransferase mice molecular mouse mutations N-terminal Natl Neurochem neuronal NF-B activation nucleotide pathway patients peptides phagocytosis Piacentini polyglutamine polymers Proc promoter protein reaction reactive receptor regulation role S-adenosylmethionine sequence shown signaling structure studies substrate subunit synuclein TGase 2 expression TGase activity TGase-2 tissue transglutaminase transamidation activity transglutaminase activity tumor vitro vivo