Pharmacology of Neuromuscular FunctionPharmacology of Neuromuscular Function, Second Edition provides information pertinent to drugs that affect membrane potentials of the conduction of action potentials in nerve endings and muscle fibers. This book reviews, in a general way, some of the properties of excitable membranes. Organized into seven chapters, this edition begins with an overview of innervation of striated muscles by somatic efferent nerve fibers. This text then explains the transmission from nerve to muscle, which is mediated by acetylcholine that is synthesized and stored in the axon terminals. Other chapters consider t ... |
Contents
Preface | 1961 |
Excitable membranes | 8 |
prejunctional events | 36 |
Copyright | |
9 other sections not shown
Other editions - View all
Common terms and phrases
acetylcholine release action potential activity addition agents agonist amplitude anaesthesia anaesthetic antagonist anticholinesterase appears atracurium axon binding block Bowman Ca2+ calcium cause cells channels choline cholinoceptors clinical compounds concentration conductance consequence contain contraction dependent depolarization depression described dose duration effect endplate enhanced enzyme et al evidence evoked example Experimental experiments fact Figure frequency illustrated important increase indicates inhibition injected interaction ions Journal Journal of Physiology known Marshall mechanism membrane potential molecules motor nerve muscarinic muscle fibres myosin neostigmine nerve endings nerve terminals neuromuscular junction neuromuscular-blocking drugs nicotinic normal occurs onset pancuronium Pharmacology plasma possible postjunctional present probably produced prolonged protein receptors recorded reduced repetitive response result reversal reviewed showed shown similar skeletal muscle sodium species stimulation structure studies toxin transmission transmitter transmitter release tubocurarine twitches vecuronium vesicles