Experimental Pharmacogenetics: Physiopathology of Heredity and Pharmacologic Responses |
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abnormal acetate acid activity adipose tissue adrenaline albino allele amino anemia animals assays BALB/c biochemical Biol blood brain breeding Cancer catalase catecholamines cells Chinese hamster cholesterol cholinesterase clotting factors coagulation compounds corticosterone cortisone decrease defect deficiency diabetes diabetes mellitus diet dilute disease dogs doses drug dystrophy effects enzyme excretion Exptl F₁-hybrids factor X fatty females fibrinogen gene genetic genotypes glucose glutamic acid guinea pigs hemophilia hemorrhagic hereditary Heredity Heston heterozygotes homozygous hormone human hyperglycemia inbred mice inbred strains inbreeding increased inherited inhibition injection insulin islet kidney laboratory lesions levels lipid litters liver males Meier metabolism mg/kg mice mouse mutant noradrenaline normal O-H mice obese obese mice observed occur pharmacologic phenformin Physiol pituitary plasma Proc protein prothrombin rabbit rats reserpine response Russell serotonin serum similar species spontaneous steroids strain differences strains of mice studies susceptibility synthesis thrombin thromboplastin thyroid tion toxicity tumors vitamin vitro Yerganian