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abnormalities acute lymphoblastic leukemia adenocarcinoma adjuvant chemotherapy adjuvant therapy agents allogeneic antibodies antigen associated autologous bone marrow B-cell Blood bone marrow transplantation breast cancer Cancer Res carcinoid carcinoma cell chromosome chronic lymphocytic leukemia cisplatin clinical colon colorectal cancer combination chemotherapy cyclophosphamide cytogenetic diagnosis disease-free survival doxorubicin drug effects Engl estrogen etoposide evaluation fluorouracil gastric cancer gene growth factor hepatic high-dose histologic Hodgkin’s disease hormonal incidence increased infusion interferon involvement irradiation lesions liver lung cancer lymph nodes M. D. Anderson malignant markers metastatic metastatic breast cancer metastatic disease methotrexate mg/m multiple myeloma mutations myelogenous leukemia Natl Cancer Inst oncogene Oncology Group ovarian cancer overall survival paclitaxel pancreatic cancer patients with stage Proc Am Soc prognostic factors prostate cancer protein radiation therapy radiotherapy randomized trial receptor rectal recurrence regimen relapse remission reported resection response rate risk Soc Clin Oncol Surg surgery surgical survival rate syndrome tamoxifen tion toxicity treatment