Developmental Neurobiology of the Autonomic Nervous SystemThis book, covering many key aspects of autonomic nervous system maturation, was suggested by the success of a symposium on the developing autonomic nervous system held at the Spring 1982 meeting of the Federation of American Scientists for Experi mental Biology (Federation Proceedings 1983, 42, 1609). It was obvi ous from the F ASEB symposium that there is increasing interest in the developing autonomic nervous system, particularly with respect to its role in regulating visceral function. Some additional topics that were not covered in the F ASEB symposium are also included in this book. The editor feels that the readers of this volume are, in all probability, already cognizant of the state of knowledge of the adult autonomic nervous system. Therefore, a review of classical autonomic physiology, pharmacology, and neuroanatomy is not provided. For a recent detailed discussion of the ontogeny and phylog eny of the developing nervous system, I would recommend the book published not long ago by D. Purves and J. W. Lichtman, Principles of Neural Development (Sinauer, Sunderland, MA, 1985). Another recent book, Autonomic Nerve Funtion in the Vertebrates by F. Nilsson (Springer-Verlag, New York, 1984), presents a compar ative examination of autonomic nervous system function in verte brates. For a summary of recent advances in the many aspects of catecholamines as they bear on autonomic nervous system re search, I would recommend the series of three books edited by E. |
Contents
| 1 | |
Establishment of Chemical Diversity in the Autonomic | 10 |
Conclusions | 18 |
Early Chemical Differentiation of Autonomic Neurons | 30 |
Stages of Chemical Differentiation of Autonomic Synapses | 40 |
Synaptogenesis in | 46 |
Biochemical Development of Neuroeffector Junctions | 54 |
References | 59 |
Acetylcholine | 173 |
ACCAMP | 180 |
Transmembrane Action Potential Characteristics | 194 |
Effects of Autonomic Nervous System Agonists | 201 |
Conclusions | 207 |
Postnatal Development | 216 |
Plasticity | 224 |
Chapter 9 | 233 |
46 | 62 |
Chapter 3 | 69 |
Role of Innervation in Onset of Adrenomedullary Function | 77 |
The Functional Significance of Adrenomedullary | 85 |
Development of Synaptic Function in | 98 |
Role of Thyroid Hormones in Development of Sympathetic | 107 |
Role of Glucocorticoids in Development of Sympathetic | 124 |
Chapter 5 | 135 |
Postganglionic Autonomic Neurons | 139 |
Receptor Development | 148 |
Chapter 6 | 159 |
Norepinephrine Uptake Mechanisms | 165 |
Responses of Isolated Blood Vessels to Autonomic | 236 |
Conclusions | 246 |
Ontogeny of SNS Control of End Organ Activity | 253 |
Ontogeny of Nonvascular Smooth Muscle Function in | 262 |
Conclusions | 274 |
Results and Discussion | 282 |
Conclusions | 318 |
Chapter 12 | 327 |
MaturationRelated Characteristics of the Respiratory | 342 |
Afferent Inputs to the RRG | 353 |
Conclusions | 378 |
Other editions - View all
Developmental Neurobiology of the Autonomic Nervous System Phyllis M. Gootman No preview available - 1986 |
Developmental Neurobiology of the Autonomic Nervous System Phyllis M. Gootman No preview available - 1986 |
Developmental Neurobiology of the Autonomic Nervous System Phyllis M. Gootman No preview available - 2013 |
Common terms and phrases
action potential activity adrenal medulla adrenergic adult afferent age-related aortic pressure apnea arteries autonomic nervous system baroreceptor biochemical Biol blood pressure Burnstock cardiac cardiovascular carotid catecholamines cervical ChAc chemoreceptor chick embryo chlorisondamine cholinergic chronotropic ciliary ganglion culture decrease density developmental differentiation Douarin effects efferent end organ enzyme factors femoral fetal fluorescence function Giacobini heart rate hypothyroidism hypoxia increase infants innervation levels maturation mechanisms mesenteric methoxamine myocardial myocardium neonatal nerve terminals nervous system neural crest cells neurons Neurosci neurotransmitter newborn noradrenergic norepinephrine NREM nucleus onset ontogeny ornithine decarboxylase parasympathetic peripheral Pharmacol Physiol piglets postganglionic postnatal postsynaptic preganglionic presynaptic preterm Purkinje fibers rabbit receptors reflex regulation renal respiratory response specific splanchnic sponses stimulation studies swine sympa sympathetic ganglia sympathetic nerve sympathetic neurons synaptic vesicles synthesis T. A. Slotkin thetic tion tissue tyramine tyrosine hydroxylase uptake vagal vascular smooth muscle vitro vivo