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acid adherent affection aged albumen albuminuria alia angina appeared ash-coloured attacked attended became Birmingham bowels breathing Bretonneau bronchial character colour complained congested convalescence cough covered croup death deglutition depression died difficulty of swallowing diph diphtheria diphtheritic exudation discharge epidemic epiglottis eruption excoriated extended false membrane feeble fibrinous filmy frequently gangrenous glands haemorrhage healthy illness inflamed inflammation larynx larynx and trachea left tonsil less lungs measles Medical Officer membranous exudation morbus mouth mucous membrane mucous surface neighbourhood nostrils observed occasionally occurred oesophagus opaque pain patches patient pellicle pharynx post-mortem examination posterior fauces present prevailed Privy Council proved fatal pulse rarely rash recovered right tonsil scarlet fever seen sequelae sick skin slight slightly sloughs soft palate sometimes sore sore-throat swelling swollen symptoms Tattershall Thorpe theria thick throat tion tissue tongue tonsils trachea tubes ulceration urine uvula velum voice wine
Page 25 - A thin white slough seems to accompany the next degree; a thick opaque or ash-colored one is a further advance, and if the parts have a livid or black aspect, the case is still worse. These sloughs are not formed of any foreign matter spread upon the parts affected, as a crust or coat, but are real mortifications of the substance ; since, whenever they come off, or are separated from the parts they cover, they leave an ulcer of greater or less depth, as the sloughs were superficial or penetrating.
Page 40 - ... shammoy leather. The inner membrane of the trachea was slightly inflamed ; the lungs too appeared inflamed, as in peripneumonic cases ; particularly the right lobe, on which there were many large livid spots, though neither rotten or offensive ; and the left lobe had small black spots on it, resembling those marks left under the skin by gun-powder.
Page 16 - Ulcers occur on the tonsils; some, indeed, of an ordinary nature, mild and innocuous; but others of an unusual kind, pestilential and fatal. Such as are clean, small, superficial, without inflammation and without pain, are mild; but such as are broad, hollow, foul, and covered with a white, livid, or black concretion, are pestilential.
Page 25 - Generally on the second Day of the Disease, the Face, Neck, Breast, and Hands to the Fingers Ends, are become of a deep erysipelatous Colour, with a sensible Tumefaction; the Fingers are frequently tinged in so remarkable a manner, that, from seeing them only, it has not been difficult to guess at the Disease. A great Number of small Pimples, of a...
Page 40 - All these symptoms continued, or rather increased, until the third night, on which she had five or six loose stools, and died early in the morning. ' Upon examining the body, which was done on the afternoon of the day she died, I found the fauces, uvula, tonsils, and root of the tongue interspersed with sloughs, which still retained their whitish colour. Upon removing them the parts underneath appeared rather pale, than inflamed. I perceived no putrid smell from them, nor was the corpse in the least...
Page 44 - The virus of the membranous exudations, according to him, forms the distinctive pathological feature of the disease. Bretonneau further asserts it to have been proved by numerous facts, that persons who attend cannot contract diphtheria unless the diphtheritic secretion, in the liquid and pulverulent state, be placed in contact with a soft or softened mucous membrane, or with the skin on a point denuded of epidermis, and this application must be immediate.
Page 25 - A great number of small pimples, of a color distinguishably more intense than that which surrounds them, appear on the arms and other parts. They are larger and more prominent in those parts of the same subject, where the redness is least intense ; which is generally on the arms the breast and lower extremities.
Page 32 - ... family, of whom two died, both being just out of the measles. The later series of cases in the winter of 1793—94 were less often fatal; the epidemic constitution, he says, became less severe towards the end ; he also used mercurials freely on the later cases ; but it is farther noteworthy that " most of the cases which occurred in November and afterwards, were attended with inflammation and swelling of the tonsils, uvula and velum pendulum palati, and frequently large films of a whitish substance...
Page 38 - ... swallowing was very little, if at all, impeded. These symptoms, with a slight fever, at night, continued in some for five or six days, without alarming their friends; in others a difficulty of breathing came on within twenty-four hours, especially in the time of sleep, and was often suddenly encreased to so great a degree as to threaten immediate suffocation. In general, however, it came on later, increased more gradually, and was not constant, but the patient would now and then enjoy an interval...
Page 39 - ... the beginning, now became much more so ; yet even when the disorder was at the worst, they retained their senses, and would give distinct answers when spoken to, although, on being left to themselves, they lay, for the most part, in a lethargic condition, only raising up now and then to re-.