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Enzyme and immobilized cell technology
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achieved activity adsorption aeration agitation amylases animal cells antibiotics applications aqueous bacteria batch biological biomass bioreactor bioreactor systems biotechnological processes biotechnology cell culture chemical chromatography chromosomes cloning coli commercial concentration contamination continuous costs Covalent cultivation developed diploid DNA fragments DNA molecules downstream processing energy enzyme production enzymes ethanol fermentation processes filamentous fungi filter filtration genes genetic engineering genetic manipulation genome glucose isomerase growth haploid hybridization immobilized cells immobilized enzymes important improve increase industrial intracellular involve isolated liquid mass transfer materials mechanical medium membrane metabolites methods microbial Microbiology microorganisms molecular monoclonal antibody mutation nutrients occur operation optimize organic acids oxygen packed bed parasexual particles penicillin phase plant cells plasmid practice product formation protein protoplast fusion protoplasts purification reactions reactor restriction endonucleases scale screening selection solid substrate fermentations specific sterilization strains Streptomyces Table techniques temperature toxic types vaccines vectors volume widely yeast