The Bacteriophages, Volume 1
Springer US, Jun 30, 1988 - Medical - 614 pages
It has been 10 years since Plenum included a series of reviews on bacte riophages, in Comprehensive Virology. Chapters in that series contained physical-genetic maps but very little DNA sequence information. Now the complete DNA sequence is known for some phages, and the se quences for others will soon follow. During the past 10 years two phages have come into common use as reagents: A phage for cloning single copies of genes, and Ml3 for cloning and DNA sequencing by the dideoxy termi nation method. Also during that period the use of alternative sigma fac tors by RNA polymerase has become established for SPOl and T4. This seems to be a widely used mechanism in bacteria, since it has been implicated in sporulation, heat shock response, and regulation of nitro gen metabolism. The control of transcription by the binding of A phage CII protein to the -35 region of the promoter is a recent finding, and it is not known how widespread this mechanism may be. This rapid progress made me eager to solicit a new series of reviews. These contributions are of two types. Each of the first type deals with an issue that is exemplified by many kinds of phages; chapters of this type should be useful in teaching advanced courses. Chapters of the second type provide comprehensive pictures of individual phage families and should provide valuable information for use in planning experiments.
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Recombination in Natural Populations
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Acad activity amino acid assembly Bacillus subtilis bacterial bacteriophage T4 baseplate binding Biol Bukhari capsid Casjens cells Christensen chromosome cleavage cloned coat gene coat protein codon Cold Spring Harbor coliphage complex containing d29 DNA deletion DNA packaging DNA replication early genes EcoRI encoded enzyme Escherichia coli fragments function Geiduschek gene product genome head homology host DNA Iida induced infection initiation insertion interaction isolated late genes located lysis lysogens lytic mechanism molecular molecules Murialdo mutants Natl nucleotide Nucleotide sequence operon particles phage d29 phage DNA plasmid polypeptide Proc prohead promoters prophage recombination region replicase replicon repressor restriction ribosomal Ritchie RNA phages RNA polymerase role Salas segment shutoff specific SPO1 Sternberg strains structure studies subtilis subunits suggested T5 DNA tail fiber template terminal protein tion transcription transducing transducing particles transposition unpublished viral virion Virol Virology virus vitro vivo