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aa bb cc agouti albino allele Animal Production Section ascites branch breeders breeding brown caries catalog cells Charac characteristics Chief coat color colony Color color genes controlled cross derived designation desired detectable determine developed differentiation disease distribution environmental eumelanin evidence exhibit experimental factor Fair female followed full-sib mating genes genetic uniformity genetic variability granules grow guinea pig hair Hamster hand hepatomas Heston High incidence highly hybrid inbred animals inbred strains Inbred Strains continued inbreeding increased intense laboratory animals leukemia lines Little locus maintained male mammary tumor incidence mating system mice Non-agouti orders Origin particular pattern phenotypic pigment Poor present Prior rabbits random bred random mated rats reduce regarding relatively reproduction reproduction rate resistant respiratory infections selection separated SPECIES Strong sublines substrains traits variance variation vigorous