Molecular Biology: A Selection of PapersSydney Brenner Founded in 1959, by John Kendrew, the Journal of Molecular Biology was the first journal devoted to this new and revolutionary science. To celebrate the thirtieth anniversary of the Journal, the current editor, Sydney Brenner, has selected a number of papers from the first hundred volumes. They include the seminal papers on genetic regulation by Jacob and Monod and on allostery by Monod, Changeux and Jacob. Also included are many important papers on structural biology and molecular genetics and papers reflecting the initial developments in DNA cloning and sequencing. Of value to all biologists with an interest in the molecular basis of living systems, the book is a personal selection by the Editor. Readers are encouraged to compare it with their own choice from the Journal of Molecular Biology. |
Contents
Preface | 1 |
A Tissičres J D Watson D Schlessinger and B R Hollingworth | 15 |
S Brenner G Streisinger R W Horne S P Champe L Barnett S Benzer | 28 |
Copyright | |
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32P-labeled Acad acetate acridine actin activity allosteric amino acid anticodon arginine assayed bacteria bacteriophage band binding Biochem Biol biophys buffer cells cellulose cellulose nitrate centrifugation chain Chem chromatographic chromosome chymotrypsin cistron codon coli concentration containing cts/min density described digest DNA molecules electron electrophoresis endonuclease enzyme Escherichia coli experiments fraction fragments galactosidase gene genetic gradient host specificity hybrid incubation inducer infected interaction ionophoresis isoleucine Khorana labeled lattice length maximum match method micrographs minus strands mixture molecular weight molecules Monod mutants myosin nucleotide obtained oligonucleotides pairs particles peak peptide phage phosphodiesterase Plate prepared present Proc proflavine prophage protein purified radioactivity recombinants region renatured repressor residue ribonuclease ribosomes samples sedimentation sequence shown solution sRNA strain structure substrate subunits superposition patterns suppressors SV40 DNA synthesis T₁ thin filaments tRNA Wash yeast µg/ml