Pathogenomics: Genome Analysis of Pathogenic Microbes
Jörg Hacker, Ulrich Dobrindt
John Wiley & Sons, Dec 13, 2006 - Science - 616 pages
The first book on this young, highly dynamic, and expanding field.
This comprehensive, interdisciplinary text focuses on those pathogenic bacteria that are of high scientific and public health interest, yet which also display great potential for the development of new diagnostic, prophylactic and therapeutic procedures.
The authors cover all aspects of pathogenomics, including methods, genomics and applications. In addition, the ongoing development of genome, transcriptome, proteome and bioinformatic analyses of pathogenic microorganisms and their host interactions makes for a comprehensive introduction to the field of modern genomic analysis.
This result is invaluable to researchers and students wishing to gain a general overview of microbial functional genome analysis and pathogenesis, while also representing a good starting point for those new to the area.
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adhesin albicans anthracis antibiotic antigens array Bacillus bacterial Bacteriol bacteriophages Bartonella Biol cereus chromosome Clin clinical comparative genomics complete genome sequence database deletion detection disease DNA microarrays drug enterica serotype enzymes epidermidis epithelial cells Escherichia coli eukaryotic evolution faecalis function gene cluster gene expression gene transfer genes encoding genetic genomic islands growth Helicobacter pylori henselae homologues host cell human identified induced Infect Immun insertion intracellular involved isolates Legionella Listeria monocytogenes macrophages meningitidis metabolic microbial Microbiol molecular mutagenesis mutants Mycobacterium Natl Acad Sci Neisseria novel nucleotide ofthe operon ORFs organisms parasite pathogenesis pathogenicity island pathways phage phenotypic phylogenetic plasmid pneumophila PrfA Proc Natl Acad prophage proteins proteome recombination regions regulation resistance response role Salmonella secretion system serogroup serotypes species Staphylococcus aureus strains Streptococcus structure studies subtilis target tion toxin transcription transposon tuberculosis Typhimurium vaccine viral virulence factors virulence genes virus viruses vivo