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ANTIGENSPECIFIC BCELL SIGNALING
GENERATION AND CHARACTERIZATION
3 other sections not shown
Acad affinity Ag-induced anti-BrMRBC anti-HEL anti-Ig antibodies antigen receptor antigen-specific B-cell activation B-cell development binding bone marrow Ca2+ Cambier cell cycle cell lines cell surface class II MHC cross-linking culture DeFranco Delespesse desensitization expression factor Figure fraction function G protein growth Hayakawa heavy chain helper T cells Herzenberg hybridomas Ig secretion Ig-transgenic mice IgM and IgD immature B cells immune immunoglobulin Immunol induced inhibition interaction interleukin ionomycin isotype Klaus lectins levels ligand light chain Ly-1 B cells lymphocytes lymphokines lymphoma mature mechanism mediated membrane IgM memory B cells mIgM molecular molecules mouse mRNA murine murine B cells Natl normal pathway phorbol esters phospholipase PIP2 PKC activation pre-B cells Proc protein kinase rearrangement regulation response resting B cells role sequences sIgD sIgM signal transduction soluble specific spleen splenic B cells stimulation supernatants surface Ig synthesis T-cell clones T-cell help Th cell transgenic tyrosine phosphorylation vitro