Drosophila Eye Development, Volume 37

Front Cover
Springer Science & Business Media, Mar 12, 2002 - Science - 282 pages
0 Reviews
1 Kevin Moses It is now 25 years since the study of the development of the compound eye in Drosophila really began with a classic paper (Ready et al. 1976). In 1864, August Weismann published a monograph on the development of Diptera and included some beautiful drawings of the developing imaginal discs (Weismann 1864). One of these is the first description of the third instar eye disc in which Weismann drew a vertical line separating a posterior domain that included a regular pattern of clustered cells from an anterior domain without such a pattern. Weismann suggested that these clusters were the precursors of the adult ommatidia and that the line marks the anterior edge of the eye. In his first suggestion he was absolutely correct - in his second he was wrong. The vertical line shown was not the anterior edge of the eye, but the anterior edge of a moving wave of patterning and cell type specification that 112 years later (1976) Ready, Hansen and Benzer would name the "morphogenetic furrow". While it is too late to hear from August Weismann, it is a particular pleasure to be able to include a chapter in this Volume from the first author of that 1976 paper: Don Ready! These past 25 years have seen an astonishing explosion in the study of the fly eye (see Fig.
 

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

Introduction
1
New Members?
12
Regulators of the Morphogenetic Furrow
18
Decapentapiegic Promotes Morphogenetic Furrow Movement
25
NOTCH and the Patterning of Ommatidial Founder Cells
35
Intermediate Group Specification and Patterning
44
Conclusions
51
Introduction
59
Developmental Regulation Through Protein Stability
151
Regulation of Ttk88 Protein Stability
153
Future Directions
164
Molecules of Death
170
Making a Hexagon
178
References
184
BasalECM Contacts
198
The Establishment of Retinal Connectivity
205

Cell Fate Specification
65
Cell Fate Specification in the Drosophila
73
Generating and Testing Combinatorial Models
83
Tissue Polarization in Development
89
How Is the Polarity Signal Interpreted Within
100
Regulation of Growth and Cell Proliferation During
107
Mechanisms That Regulate Growth and Cell Proliferation
119
Concluding Remarks
128
Evolution of Color Vision
135
Spectral Organization of the Fly Retina
141
Signal Transduction in Photoreceptor Axon Growth Cones
214
The Expression Pattern of Regulatory Genes
222
Eye Morphogenesis
228
Retinal Differentiation
235
Evolution and Homologies
248
Applications of the Drosophila Retina to Human Disease Modeling
257
Phototransduction Cascade Mutants
262
Concluding Remarks
270
Copyright

Other editions - View all

Common terms and phrases