Genomic Diversity: Applications in Human Population Genetics ; [proceedings of a Symposium on Molecular Anthropology in the Twenty-First Century, Held During the 14th International Congress of the Association of Anthropological and Ethnological Sciences, Held July 26 - August 1, 1998, in Williamsburg, Virginia]

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Surinder Singh Papiha, Ranjan Deka, Ranajit Chakraborty
Springer Science & Business Media, Oct 31, 1999 - Medical - 246 pages
One of the major themes of human population genetics is assaying genetic variation in human populations. The ultimate goal of this objective is to understand the extent of genetic diversity and the use of this knowledge to reconstruct our evolutionary history. The discipline had undergone a revolutionary transition with the advent of molecular techniques in the 1980s. With this shift, statistical methods have also been developed to perceive the biological and molecular basis of human genetic variation.
Using the new perspectives gained during the above transition, this volume describes the applications of molecular markers spanning the autosomal, Y-chromosomal and mitochondrial genome in the analysis of human diversity in contemporary populations. This is the first reference book of its kind to bring together data from these diverse sets of markers for understanding evolutionary histories and relationships of modern humans in a single volume.
 

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Contents

CLASSICAL TO MOLECULAR POLYMORPHISMS Population Genetic Studies from the Indian SubContinent
1
VARIABILITY IN nDNA mtDNA AND PROTEINS A Test Case
23
GENETIC DIVERSITY AMONG FIVE NATIVE AMERICAN TRIBES OF COLOMBIA Evidence from Nine Autosomal Microsatellites
33
TRINUCLEOTIDE REPEATS GENETIC INSTABILITY AND VARIATION IN THE HUMAN GENOME
53
YCHROMOSOMAL DNA MARKERS
65
ON THE GENETIC ORIGIN OF THE TURKS Study of Six YChromosomal Short Tandem Repeats
75
THE ORIGINS OF PAKISTANI POPULATIONS Evidence from Y Chromosome Markers
83
THE USE OF YCHROMOSOMAL DNA VARIATION TO INVESTIGATE POPULATION HISTORY Recent Male Spread in Asia and Europe
91
THE PLACE OF THE INDIAN MITOCHONDRIAL DNA VARIANTS IN THE GLOBAL NETWORK OF MATERNAL LINEAGES AND THE PEO...
135
MITOCHONDRIAL DNA VARIATION IN THE SOUTHWEST PACIFIC
153
MOLECULAR ANTHROPOLOGY Progress and Perspectives on Ancient DNA Technology
181
INTERSPERSED REPEAT INSERTION POLYMORPHISMS FOR STUDIES OF HUMAN MOLECULAR ANTHROPOLOGY
199
WORLDWIDE DISTRIBUTION OF A POLYMORPHIC Alu INSERTION IN THE PROGESTERONE RECEPTOR GENE
211
STATISTICAL ISSUES REGARDING THE USE OF MICROSATELLITE LOCI FOR MOLECULAR ANTHROPOLOGICAL STUDIES
217
EPILOGUE
231
Corresponding Authors
235

A MITOCHONDRIAL DNA DATABASE Applications to Problems of Nomenclature and Population Genetics
103
THE TRANSCAUCASUS AND THE EXPANSION OF THE CAUCASOIDSPECIFIC HUMAN MITOCHONDRIAL DNA
121
INDEX
237
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