Genomic Diversity: Applications in Human Population Genetics ; [proceedings of a Symposium on Molecular Anthropology in the Twenty-First Century, Held During the 14th International Congress of the Association of Anthropological and Ethnological Sciences, Held July 26 - August 1, 1998, in Williamsburg, Virginia]Surinder Singh Papiha, Ranjan Deka, Ranajit Chakraborty One of the major themes of human population genetics is assaying genetic variation in human populations. The ultimate goal of this objective is to understand the extent of genetic diversity and the use of this knowledge to reconstruct our evolutionary history. The discipline had undergone a revolutionary transition with the advent of molecular techniques in the 1980s. With this shift, statistical methods have also been developed to perceive the biological and molecular basis of human genetic variation. Using the new perspectives gained during the above transition, this volume describes the applications of molecular markers spanning the autosomal, Y-chromosomal and mitochondrial genome in the analysis of human diversity in contemporary populations. This is the first reference book of its kind to bring together data from these diverse sets of markers for understanding evolutionary histories and relationships of modern humans in a single volume. |
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Contents
CLASSICAL TO MOLECULAR POLYMORPHISMS Population Genetic Studies from the Indian SubContinent | 1 |
VARIABILITY IN nDNA mtDNA AND PROTEINS A Test Case | 23 |
GENETIC DIVERSITY AMONG FIVE NATIVE AMERICAN TRIBES OF COLOMBIA Evidence from Nine Autosomal Microsatellites | 33 |
TRINUCLEOTIDE REPEATS GENETIC INSTABILITY AND VARIATION IN THE HUMAN GENOME | 53 |
YCHROMOSOMAL DNA MARKERS | 65 |
ON THE GENETIC ORIGIN OF THE TURKS Study of Six YChromosomal Short Tandem Repeats | 75 |
THE ORIGINS OF PAKISTANI POPULATIONS Evidence from Y Chromosome Markers | 83 |
THE USE OF YCHROMOSOMAL DNA VARIATION TO INVESTIGATE POPULATION HISTORY Recent Male Spread in Asia and Europe | 91 |
THE PLACE OF THE INDIAN MITOCHONDRIAL DNA VARIANTS IN THE GLOBAL NETWORK OF MATERNAL LINEAGES AND THE PEO... | 135 |
MITOCHONDRIAL DNA VARIATION IN THE SOUTHWEST PACIFIC | 153 |
MOLECULAR ANTHROPOLOGY Progress and Perspectives on Ancient DNA Technology | 181 |
199 | |
WORLDWIDE DISTRIBUTION OF A POLYMORPHIC Alu INSERTION IN THE PROGESTERONE RECEPTOR GENE | 211 |
STATISTICAL ISSUES REGARDING THE USE OF MICROSATELLITE LOCI FOR MOLECULAR ANTHROPOLOGICAL STUDIES | 217 |
EPILOGUE | 231 |
Corresponding Authors | 235 |
A MITOCHONDRIAL DNA DATABASE Applications to Problems of Nomenclature and Population Genetics | 103 |
THE TRANSCAUCASUS AND THE EXPANSION OF THE CAUCASOIDSPECIFIC HUMAN MITOCHONDRIAL DNA | 121 |
INDEX | 237 |
Other editions - View all
Genomic Diversity: Applications in Human Population Genetics Surinder Singh Papiha,Ranjan Deka,Ranajit Chakraborty No preview available - 2012 |
Genomic Diversity: Applications in Human Population Genetics Surinder Singh Papiha,Ranjan Deka,Ranajit Chakraborty No preview available - 2011 |
Common terms and phrases
9-bp deletion admixture aDNA African allele frequencies Alu element Alu insertion amplification analysis ancestral ancient Arsario and Kogui Asia Bandelt Batzer Biol Biology blood group Caucasian Cavalli-Sforza Chakraborty Colombian tribes contamination Coreguaje D-loop database Deininger Deka detected distribution DNA sequence Eurasian Europe European evolutionary expansion fragment gene genetic variation Genomic Diversity genotype geographic haplogroup haplogroup 3 chromosomes haplotypes heterozygosity Hum Genet human genome human mitochondrial Human Population Genetics identified Ijka Indian individuals Kivisild Kogui lineage clusters locus Makrani microsatellite microsatellite loci migration mitochondrial DNA modern humans molecular mtDNA lineages mutation rate Native American node nucleotide origin Papiha phylogenetic polymorphisms Popondetta Population Genetics primers protein repeat loci RFLP Richards Salzano samples short tandem repeats Sinhalese Stoneking studies sub-cluster Surui Table tandem repeats tion Torroni trinucleotide repeat Tyler-Smith U.S. Native Americans variability VNTR Wallace DC Wayuu WNTR Y chromosome Y-chromosomal