Functional Microbial GenomicsFunctional Microbial Genomics, edited by two leading experts in the field, provides the researcher with an up-to-date collection of articles on post-genome technologies central to studying the function of microorganisms. Since the release of the first complete genome sequence of a free-living organism in 1995, over 100 microbial genomes have been completely sequenced. The advent of new technologies for post-genomic analyses has allowed the rapid exploitation of this genome sequence information, heralding a golden era in microbial research. Functional Microbial Genomics provides in-depth accounts from scientists working with these new technologies explaining both the techniques and the ways in which they have been applied to the study of gene function in different microbial species. Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Established for over 30 years, Methods in Microbiology will continue to provide you with tried and tested, cutting edge protocols to directly benefit your research. * Bioinformatic approaches to genome sequence analysis * Details the design, construction and applications of DNA microarrays * Covers advances in bacterial proteome and metagenome analysis * Describes functional genomic approaches for novel antibiotic target and vaccine candidate discovery * Presents case studies where functional genomic analyses have revolutionized our understanding of model species |
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Contents
Annotation of Microbial Genomes | 23 |
The Atlas Visualization of Genomewide Information | 49 |
Construction of DNA Microarrays | 65 |
Copyright | |
17 other sections not shown
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Common terms and phrases
acid activity addition allow amplification analysis application approach array Bacillus bacterial binding biological cDNA cell chromosome clones coli compared complex construction containing culture database described detection determine developed domain encoding essential et al example experiments Figure fragments function gene expression genetic genome sequence growth Helicobacter pylori homologous host human hybridization identified important indicate infection insertion integration interactions involved isolated labelled method microarray microbial Microbiol mutagenesis mutants Nature organisms parasites pathogens PCR products performed plasmid pool positive potential predicted present primer promoter protein proteome reaction regions regulated relative repeats reporter represent response revealed sample Science screening selection signal silico similar single specific strains structure subtilis target technique tion transcription transformation two-hybrid vector yeast
Bibliographic information
| Title | Functional Microbial Genomics Volume 33 of Methods in Microbiology |
| Contributors | Brendan Wren, Nick Dorrell |
| Publisher | Elsevier Science, 2002 |
| Original from | University of Illinois at Urbana-Champaign |
| Digitized | Jan 31, 2019 |
| ISBN | 0125215339, 9780125215336 |
| Length | 428 pages |
| Subjects | › › Science / Life Sciences / Microbiology |
| Export Citation | BiBTeX EndNote RefMan |