Biomedical and Dental Applications of Polymers
The development and use of medical and dental materials are highly interdisciplinary endeavors which require expertise in chemistry, materials science, medicine and/or dentistry, mechanics and design engineering. The Symposium upon which this treatise is based was organized to bring members from these communities together to explore problems of mutual interest. The biomaterials which are used in medical or dental prostheses must not only exhibit structural stability and provide the desired function, but they must also perform over extended periods of time in the environment of the body. The latter is a very stringent requirement. The oral and other physiological environments are designed by nature to break down many organic substances. Also of importance is the requirement that materials used in the prosthesis not have a deleterious effect on body tissues. Most foreign (to the body) substances are somewhat toxic to human tissues; in fact, few factors are more limiting in the medical prosthesis field than the biocompatibility problem. Some of these problems and the attempts to solve them are discussed in this volume.
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Selected Examples of Pathologic Processes Associated
The Status of Olefins02 Copolymers as Biomaterials
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5)-vinylimidazole acid acrylic acrylic acid activity adhesion adsorption agent amines amino apolar applications aqueous biocompatibility biolized biological biomaterials Biomed biomedical BIS-GMA blood compatibility bonding carbodiimide carboxyl groups cells cement Chem chemical clinical coated collagen composite restorative compounds concentration containing copolymer coupling efficiency crosslinking cured Dacron Dent dental composites dental materials denture base developed dextran dimethacrylate dosage forms effect electron Figure filler Gebelein glass glycol graft heparin hydrogel hydrolysis imidazole implants increase interactions interface liquid matrix mechanical membrane methacrylate methyl methacrylate mg/ml molecular weight monomers MTX-BSA Organs oxygen particles Pitha Plastics platelet poly poly(amido-amines polyelectrolytes polyether polymer polymeric polymeric drugs polypropylene glycol properties prostheses protein pump Quartz R. L. Bowen reaction release resin samples shown Silane Silastic soluble solution solvent structure studies substrate surface synthesis Table therapeutic systems thrombogenic thromboresistance thrombus tissue Trans urea urethane vinyl vivo