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Inhibition of Ionic Currents in Myelinated Nerves by Quaternary
Rate and Site of Action of Local Anesthetics in Myelinated Nerve
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acetylcholine acid action potential activity amiloride anesthesia Anesthesiology anesthetic action anesthetic agents anesthetic molecules anesthetic potency animals antagonism axonal B. R. Fink barbiturates bilayer membranes Biochem Biol block calcium cell cerebral chloroform conductance correlation cortex curve cyclic AMP decrease depolarization depression dibucaine diethyl ether doses drugs effect of halothane effects of anesthetics enzyme ethanol ether experiments frog function GABA gases glutamate halothane helium hydrophobic increase incubation inhibition interaction ions lidocaine lipid lipoproteins luciferase measured mechanism metabolism methoxyflurane microfilaments microtubules Miller mitochondria molecular monolayer morphine muscle narcosis nerve neurons observed oxygen Paton pentobarbital permeability Pharmacol phase phosphate phospholipid Physiol postsynaptic pressure reversal presynaptic Proc Progress in Anesthesiology propranolol protein Quastel rat brain receptor release response sciatic nerve Seeman sodium solubility solution studies synaptic transmission Table temperature tetracaine tetrodotoxin thetic tion tissue transmitter uptake values vesicles vitro vivo volume