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Analgesic Agents That Act Centrally to Modify
4A The Use of Steroidal Agents in the Oral Route
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Acad Sci activity acute administration adverse reactions agents allopurinol analgesic Ann Intern Ann NY Acad Ann Rheum antibody antigen antimalarials Arthritis Rheum aspirin associated auranofin autoimmune azathioprine cartilage cells chloroquine chronic chrysotherapy clinical controlled corticosteroids cyclophosphamide cyclosporine cytotoxic daily dose decreased dimethyl sulfoxide DMSO double-blind efficacy Engl enzymes excretion gastrointestinal glucocorticoids gouty hepatic high-dose hydroxychloroquine hyperuricemia ibuprofen immune immunosuppressive improvement increased indomethacin inflammation inflammatory inhibition joint Lancet levels lymphocyte metabolism methotrexate methylprednisolone mg/day months nonsteroidal anti-inflammatory drugs NSAIDs occur oral orgotein osteoarthritis pain parenteral patients receiving patients treated patients with rheumatoid penicillamine phenylbutazone placebo plasma prednisone prostaglandin proteinuria pulse steroid pulse therapy reduced regimens remission reported response Rheum rheumatic diseases rheumatoid arthritis Rheumatol salicylate serum side effects sodium steroids sulindac suppl syndrome synovial synthesis systemic lupus erythematosus therapeutic tion toxicity treatment of rheumatoid trial ulcer urate uric acid uricosuric vitro weeks