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Radiolysis of DNA studied by HPLgel chromatography
A method for detection of hydroxyl radicals in the vicinity of biomolecules using radiation
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aberrations acid apoptosis aqueous solution assay ataxia-telangiectasia biomolecules bone marrow Cancer cell cycle cell lines cell survival cellular chemical chromatin chromosome concentration cultures curve cytokines DNA damage DNA fragmentation dose-rate double-strand breaks effect el al electron electrophoresis enzyme experiments exposure fibroblasts Figure filter elution fluorescence fraction free radicals frequency GM-CSF Goodhead HAT medium human hyperthermia Iliakis inactivation increase incubated induced inhibition International Journal ionizing radiation irradiation Journal of Radiation kinetics lesions levels low doses lymphocytes mammalian cells measured medium membrane mice molecular mouse mutation neutrons normal observed oncogenic Oncology post-irradiation protein Radiation Biology Radiation Research radiation-induced Radiobiology radiolysis radioresistant radiosensitivity radiotherapy reaction recovery repair response RNA synthesis samples scid SECCA sensitivity spectra splenocytes stem cells strand breaks studies temperature thymine thymine glycol thymocytes tion tissues treatment trolox tumour tyrosine unirradiated values vitro vivo X-irradiation X-rays y-rays