Isolation, Characterization, and Utilization of T Lymphocyte ClonesIsolation, Characterization, and Utilization of T Lymphocyte Clones is a summary of information regarding T lymphocyte clones, including their usefulness. Organized into nine parts, the book begins with discussions on the soluble factors that can influence the growth of cloned T cells and the utilization of T cell hybridomas for analysis of T cell functions, emphasizing the biochemical and functional properties of helper and suppressor factors. The book then looks into the analysis of T cell clones and hybridomas using techniques of somatic cell genetics. The clonal analysis by limiting diluti ... |
Contents
Biochemical Characterization of Interleukin2 | 21 |
Production and Assay of Interleukin1 IL1 | 41 |
Production and Properties of Human IL2 | 57 |
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alloantigens allogeneic alloreactive analysis antigen antigen-specific assay biochemical Boehmer Braciale cell clones cell growth factor cell hybridomas cell lines cell populations characterization chromosomes clonal cloned T cells Con-A cross-reactivity CTL clones CTL lines CTL-B CTL-P culture cytolytic cytolytic activity cytolytic T lymphocytes cytotoxic T cells cytotoxic T lymphocytes derived determinants expression Fathman frequency function gene genetic Gillis Glasebrook H-2 restricted haplotype helper cells Hengartner human hybridomas idiotype IL-2 activity IL-2 production immune response Immunol Immunology induced inhibition interaction interleukin irradiated isolated limiting dilution Lonai LYMPHOCYTE CLONES lymphoid cells lymphokines lysis macrophages medium MHC restricted mice mitogen molecules monoclonal antibodies mouse murine Nabholz Nature London precursors present proliferation protein reactive recognition release repertoire specific spleen cells stimulator cells studies supernatant suppression suppressor factor suppressor T cells syngeneic T-cell Table target cells TCGF thymocytes tion variants vitro vivo µg/ml