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17 German regions Aachen Analyse der Stromwirtschaft Audretsch BioRegio Jena BioRegio-contest initiated biotech firms biotech research biotechnology industry BMBF Boehringer Mannheim bundling research efforts central government intervention cluster contest countries criteria Daniel PIAZOLO development concept efficiency by bundling Ergas Ernst and Young European biotech industry Federal Research Ministry finance German innovation system German technology policy governance problem Greifswald groups of firms Heidelberg high tech industries Horst SIEBERT human capital incentives Juli Juni KIEL WORKING PAPERS Klodt knowledge spillovers Ludwigshafen market failure million DM mission-oriented model regions Munich national government national technology policy Number overall economic point positive externalities process and stimulates public funds R&D-expenditures in Germany Regensburg Regional Consequences regional development policy regional economic point regions as relevant research institutes respective regions Rhine-Neckar Triangle Rhineland role Rostock second noteworthy change September 1998 spatial proximity stimulates interregional competition Storper subsidization technology policy initiatives technology-regions connection units for technology venture capital Wuppertal