Molecular Basis of Cdc42-mediated Cell Proliferation and Regulation of ApoptosisCornell University, 2003 - 344 pages |
Contents
Cdc42 is a substrate for caspase | 30 |
Antiapoptotic Cdc42 mutants | 81 |
Activation and localization of Cdc42 is regulated | 118 |
Copyright | |
1 other sections not shown
Common terms and phrases
3T3 cells actin activated Cdc42 activation of Cdc42 active Src analyzed by Western anti-apoptotic anti-HA antibody apoptosis apoptotic apoptotic signals apoptotic stimuli aprotinin aspartic acid assayed Biol Chem caspase caspase activation caspase-3 caspase-catalyzed catalyze Cdc42 and Rac Cdc42 molecules Cdc42 mutants Cdc42-mediated cell growth cell lines cells expressing Cerione constitutively active Src(Y527F Cos-7 cells Covance cycle degradation of Cdc42 DMEM domain EGF receptor EGF stimulation EGF-dependent EGFR Empty Vector enhanced exchange GDP Fas ligand fast-cycling fibroblasts GDP for GTP GST-PBD GTP hydrolysis GTP-binding proteins GTP-bound GTPase GTPase-defective guanine HA-antibody hydrolysis incubated inducing cellular transformation inhibit IQGAP Lysates NIH 3T3 NIH3T3 cells oncogenic panel shows pathways phosphorylation of Cdc42 precipitated proteolysis regulation residue RhoGDI stably expressing substrate survival switch target/effectors transfected transiently express transiently transfected tyrosine 64 tyrosine kinase tyrosine phosphorylation Vav2 Western blot analysis Western blotting wild-type Cdc42 µg/mL