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HEPATITIS B VIRUS IMMUNOPATHOGENESIS Francis V Chisari
PEPTIDE ANTIBIOTICS AND THEIR ROLE IN INNATE IMMUNITY Hans
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Acad activation addition AIDS animals antibody antigen appears associated binding Biol blood CD4+ T cells CD8+ cells channels clones complement complex contain cytokines cytoplasmic cytotoxic demonstrated dependent determined diabetes differentiation disease domain donor early effects enhanced evidence expression factor Figure function gene genetic hepatitis host human identified IFN-y immune response Immunol important increased indicated induced infection inhibits initial interaction involved kinase levels ligand lines lymphocytes macrophages major mature mechanism mediated membrane MHC class mice molecules mouse murine Nature negative normal observed pathway patients peptide positive selection possible present Proc production protein recently receptor region regulation residues role Science secretion sequence SH2 domains showed side signaling similar specific stimulation strains structure studies suggest thymocytes tion transcription transgenic tumor tyrosine viral virus vitro vivo