Artificial Kidney, Artificial Liver, and Artificial Cells

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T. Chang
Springer Science & Business Media, Dec 6, 2012 - Medical - 316 pages
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There is a rapid increase in interest related to novel approaches in artificial kidneys, artificial liver, and detoxifi cation. Recent research has included the successful clinical appli cations of the principle of artificial cells for adsorbent hemo perfusion. Since it is 20 years ago at McGill that the first report on "Artificial Cells" was presented, I thought it might be useful to get together a small group of speakers and participants for a day before the ASAIO meeting to discuss some recent advances in the area of the clinical applications of artificial kidney, artificial liver and artificial cells with emphasis on adsorbent hemoperfusion. However, the enthusiastic supports of distinguished speakers, session chairmen and participants were such that the original pro jection of 100 participants had expanded to a preregistration total of 250, from Australia, Canada, England, France, Germany, Israel, Italy, Japan, The Netherlands, Scotland, Sweden and U. S. A. The program also expanded to include a review section on hemodialysis, dialysate regeneration, hemofiltration, resin hemoperfusion and oxystarch given by their respective originators. The remaining of the symposium emphasizes the status of the art on different encap sulated adsorbent hemoperfusion approaches. I would like to apolo gize to those who we could not accommodate beca~se of space limita tions. It is hoped that this symposium volume may be useful for them and for others who are interested in this area. Special thanks are due to Ms Joanne Toms for her excellent secretarial assistance for the conference and Mrs.
 

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Contents

Address of Welcome
2
The Present Status and Perspectives of Hemodialysis
11
Current Status of Dialysate Regeneration
23
Devising a Practical Suitcase Hemodialyzer
33
Present Status of Hemofiltration
39
The Present
47
Artificial Cells for Artificial Kidney
57
Microencapsulated Charcoal Hemoperfusion
69
Hemoperfusion and Removal of Endogenous
153
Charcoal Hemoperfusion in Mushroom
165
Biocompatibility Studies of Hemoperfusion
173
The Use of Membranes and Sorbents for Blood
185
Combination of Hemodialysis and Hemoperfusion
193
FixedBed Charcoal Hemoperfusion in
209
Experience with Resin Hemoperfusion
217
Strathclyde Approach Towards Artificial
225

Clinical Experience of BeadShaped Charcoal
79
Hepatic Assist System Using BeadType Charcoal
89
Extracorporeal Immunoadsorbents for Specific
99
Evaluation of Charcoal Hemoperfusion in Uremia
107
Georgetown University
117
Treatment of Fulminant Hepatic Failure
125
Use of Activated Adsorbent Haemoperfusion
135
Clinical Experience with CelluloseCoated Carbon
143
Assessment of Two Rat Models of Fulminant
239
Conversion of Urea and Ammonia to Amino Acid
249
Molecular Sieve
267
Chronic Renal Failure and Future Approaches
277
Treatment of Acute Intoxication
293
General Discussion
301
Index
309
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