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activated carbon ajmaline alginate amino acids anaerobic antibiotic aspartic acid bacteria batch biocatalyst Biochem biological biomass bioreactor Biotechnol Biotechnology broth Chem chemical cloning coli compounds concentration containing cultivation D-HicDH Dechema Dechema Biotechnology Conferences decrease degradation dehydrogenase efficiency endoglucanase entrapped enzymatic enzyme ethanol experiments extraction fermentation fixed bed reactors flow formation gene genetic genome glucose growth herbicides hybrid hybrid plasmids hydrolysis immobilized increased inhibitors investigated isolated kinetics levan lipase loop reactor measured medium membrane methods microbial Microbiol microorganisms molecular mutants nitrate obtained operation organic oxygen oxygen transfer parameters particles phages phase phenol photosystem plasmid production protein Pseudomonas Pseudomonas putida reaction recombinant reduced Rehm sequence sludge solution specific strains Streptomyces Streptomyces albus structure substrate sucrose sulfur source synthesis temperature Universitat VCH Verlagsgesellschaft 1988 vector velocity waste water yeast yield