Man Adapting

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Yale University Press, 1980 - Medical - 538 pages
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This enlarged edition of Man Adapting includes a new chapter expanding Dr. Dubos's discussion of the role of medicine in man's adaptive processes.  In 1965 he wrote at length of the biological and social problems of human adaptation, while treating the medical aspects of this problem only in passing.  He believed that the goal of medicine was to help man function successfully with the particular circumstances of his environment and heredity.  But despite advancements in the prevention and treatment of disease, skepticism has developed during the last two decades concerning the usefulness of modern medicine.  Dr. Dubos turns here to readdress this question.

Today physicians rely on sophisticated scientific knowledge, and no longer offer the traditional doctor-patient relationship which ministered to psychological as well as physical comfort.  But it is this spiritual aspect of human medicine, Dr. Dubos argues, which distinguishes it from general biology, and it will retain its unique position among the sciences only if it accepts responsibility for the human aspects of life.  Dr. Dubos demonstrates the complex interrelationship between man and his biological environment.  He writes, "I have attempted to focus my attention on the individual human being . . . trying as best he can to meet the emergencies of the day and to prepare for the uncertainties of the future.  He is Man Adapting."
 

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Contents

Mans NATURE
1
MAN IN THE PHYSICAL WoRLD
35
Biological rhythms
42
Seasonal ketonuria in fasting rats
46
Time displacement of potassium urinary excretion in man
53
Bioclimatology
56
Mans Food
63
Estimated minimum daily protein intake for man
67
Mean and maximum concentrations of selected particulate contaminants
208
Biological effects of air pollutants
209
USA air quality standards and threshold limit values for solids or liquids
210
California air quality standards specifications and threshold limit values for gases and vapors
212
Data on which German VDI air quality specifications are based
213
Registered deaths in London administrative county by age comparison of sevenday period before the 1952 episode with the sevenday period that inc...
214
Delayed and indirect effects of biologically active agents
220
CHANGING PATTERNS OF DISEASE
226

Composition of INCAP vegetable mixture 8
74
Nutritional state and development
77
Nutritional adaptations
81
THE LIVING WoRLD
88
The social environment
100
THE INDIGENOUs MICROBIOTA
110
Digestive flora of NCS mice
115
Bacterial colonies recovered 3 weeks after feeding bacterial cultures to germfree mice
116
Comparative fecal flora of two strains of Swiss mice
117
Viable fecal flora of infants
120
Alteration of the fecal flora by penicillin
127
Effects of the microbiota on host nutrition
128
Physiological effects of the indigenous microbiota
140
NUTRITION AND INFECTION
147
Effect of lysine and threonine on the rate of recovery from loss of weight
154
Effect of dietary protein on susceptibility of mice to tuberculosis
155
Effect of amino acids on susceptibility to infection
156
Nutrition and dental caries
160
Exogenous vs endogenous microbial disease
176
Genetic factors in microbial diseases
185
ENVIRONMENTAL POLLUTION
196
Typical concentration values for gases and vapors in urban air
205
Air contaminants
206
Total emission of air contaminants to the atmosphere
207
Comparative life span of man and animals
228
Average remaining lifetime at specified ages
230
Social patterns of disease
236
ADAPTATION AND ITS DANGERs
254
The adaptive potentialities of man
269
THE PopULATION AvALANCHE
280
The determinants of human birth rates
301
Comparative birth rates in different parts of the world
310
Population density and human life
312
HIPPocRATES IN MoDERN DRESS
319
Organismic and environmental biology
330
MAN MEETS HIS ENVIRONMENT
344
ERADICATION VERSUS CONTROL
369
THE CONTROL OF D1s EASE
392
MEDICINE ADAPTING
419
Dilemmas of modern medicine
426
Stability vs adaptability of scientific institutions
438
The health of the people
448
CURING HELPING CONSOLING
457
BIBLIOGRAPHY
467
INDEx
520
344
523
399
531
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About the author (1980)

Rene Dubos was a famous microbiologist, as well as a writer, educator, and environmentalist. Born and educated in France, Dubos came to the United States in 1924 to join the research staff of Rutgers University. In 1927 he was invited to join the staff of Rockefeller University, where he spent practically his entire career. At Rockefeller University, Dubos pioneered research in antibiotics for commercial use during the 1940s. In 1939 he discovered tyrothricin, the first commercially produced antibiotic. As he grew older, his interests shifted from microbiology to humanistic and social-environmental issues. He devoted much of his writing to environmental problems and their impact on human beings. Dubos served as president of several professional organizations in the sciences, wrote 20 books, and was awarded more than a score of prizes by the scientific community. As an emeritus professor at Rockefeller University he continued to write until his death.