Organic Synthesis: Concepts and Methods
Since it is one of the core disciplines, every student of organic chemistry will need to cover organic synthesis at some point. This third edition of an extremely well-received and proven textbook is specially written with advanced undergraduate and graduate students in mind, although it is equally useful for research chemists, too. 50% of the text is new and includes new chapters on combinatoric chemistry, non-covalent molecular assemblies and the use of the Internet for searching chemical compounds. The authors have chosen the methods included here for their efficiency, elegance, and didactic value and have highlighted important reactions within the text.
From reviews of the second edition:
'The text is very readable, and the authors are especially gifted at explaining complex concepts clearly and succinctly...This book is highly recommended reading for anyone wishing to gain an overview of organic synthesis.' J. Am. Chem. Soc.
With his preface, Noble prizewinner E. J. Corey has also endorsed this already highly acclaimed work.
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Retrosynthetic Analysis Sketches of Syntheses
Functional Group Interconversion FGI
Heterocycles and Arenes
Biopolymers and Dendrimers
Combinatorial Mixtures and Selection
Concepts in NanometerSized Skeletons and Modules
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acetic achieved acid activated added addition alcohols aldehydes alkenes alkyl allylic amide amines amino anion applied base carbon atom carbonyl catalyst Chem chemistry chiral chloride chromatography complex compounds containing converted COOEt COOH COOMe coupling cyclization derivatives double bond electron enolate ester ethers example formation formed functional groups give given glycosyl Grignard reaction halides highly hydrogen important ketones leads less lithium MeOH metal method methyl mixture mmol molecular molecules nitrogen nucleophilic obtained occurs OH OH olefins organic oxidation peptide porphyrin prepared presence procedure protected protecting group reaction reactive reagents rearrangement reduction removed resulting ring selective solution solvents stable starting steps stereoselective structures substituted synthesis temperature terminal tion treatment units usually yield ОН