The IACUC Handbook, Second Edition

Front Cover
Jerald Silverman, Mark A. Suckow, Sreekant Murthy
CRC Press, Oct 4, 2006 - Medical - 680 pages
Since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare oversight within research institutions in the United States.

By addressing questions and problems that often confront institutions, The IACUC Handbook, Second Edition provides accurate, succinct answers. It features comprehensive updates for all pertinent federal laws, regulations, and policies. It also contains an expanded survey of IACUC practices from institutions around the nation.

With accessible information, this new editionprovides a foundation for those attempting to understand and implement the many and varied responsibilities of these committees.

 

Contents

Origins of the IACUC
1
Circumstances Requiring an IACUC
11
Creation of an IACUC
19
Reporting Lines of the IACUC
31
General Composition of the IACUC and Specific Roles of the IACUC Members
37
Frequency and Conduct of Regular IACUC Meetings
61
General Format of IACUC Protocol Forms
83
Submission and Maintenance of IACUC Protocols
93
Occupational Health and Safety
359
Personnel Training
379
Confidential and Proprietary Information
407
General Concepts of the Facility Inspection and Program Review
429
Inspection of Animal Housing Areas
455
Inspection of Individual Laboratories
469
Inspection of Surgery Areas
479
Assessment of Veterinary Care
493

General Concepts of Protocol Review
113
Amending IACUC Protocols
139
Continuing Review of Protocols
149
Justification for the Use of Animals
157
Justification of the Number of Animals to Be Used
175
Animal Acquisition and Disposition
189
Animal Housing and Use Sites
227
Pain and Distress
241
Euthanasia
287
Surgery
321
Antigens Antibodies and Blood Collection
345
Laboratory Animal Enrichment
521
Animal Mistreatment and Protocol Noncompliance
543
Postapproval Monitoring
571
Animal Welfare Act
593
Animal Welfare Act Regulations
595
Health Research Extension Act of 1985 RL 99158 November 201985 Animals in Research
603
Public Health Service Policy on Humane Care and Use of Laboratory Animals
605
US Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing Research and Training
613
Index
615
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