Microbe-vector Interactions in Vector-borne Diseases
S. H. Gillespie, G. L. Smith, A. Osbourn
Cambridge University Press, May 6, 2004 - Science - 383 pages
Several billion people are at daily risk of life threatening vector-borne diseases such as malaria, trypanosomiasis and dengue. This volume describes the way in which the causal pathogens of such diseases interact with the vectors that transmit them. It details the elegant biological adaptations that have enabled pathogens to live with their vectors and, in some circumstances, to control them. This knowledge has led to novel preventative strategies in the form of antibiotics and new vaccines which are targeted not at the pathogen itself but at its specific vector.
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activity Aedes aegypti Aedes albopictus African Anopheles gambiae antigen arboviruses arthropod bacteria Beaty Biomphalaria blood meal bluetongue Borrelia burgdorferi cellular Crosse virus Culex Culicidae Culicoides cycle defensin dengue Dimopoulos Diptera dissemination Drosophila effect encapsulation encephalitis virus encoded Entomol equine factors feeding fever virus filarial flaviviruses flea gene genetic genome glycoprotein Gubler haemocoel haemocytes haemolymph hemocytes human immune response innate immunity Insect Biochem interactions invertebrate involved Ixodes lectins Lyme disease malaria mammalian mechanisms Mellor membrane midgut molecular molecules mosquito mosquito cells mosquito vector nematodes neutrophils occur Ornithodoros Parasitol pathogens pathway peptides phagocytophilum plant viruses Plasmodium populations Proc Natl AcadSci prolixus protein Ratcliffe reassortment receptors Rhodnius RNA silencing role salivary glands sequence species spirochete strains studies susceptibility temperature tick-borne ticks tissues transgenic transmitted transovarial transmission triseriatus Trypanosoma tsetse vaccine vector vector competence vector-borne diseases vertebrate host viral Virol WEEV Wolbachia yellow fever
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