Allergic Contact Dermatitis: The Molecular BasisJean-Pierre Lepoittevin, David A. Basketter, An Goossens, Ann-Therese Karlberg Allergic Contact Dermatitis presents all up-to-date chemical and physio-chemical concepts for the study and understanding of allergic contact dermatitis (ACD). The book covers all aspects of ACD - skin penetration and metabolism, identification of sensitizers and hapten-protein interaction, including new concepts of increasing importance such as molecular recognition and quantitative structure-activity relationships. In addition, comprehensive references are provided, making this the most complete available text-book for dermatologists. Allergic Contact Dermatitis reaches an equilibrium between fundamental concepts and clinical applications and thus presents an essential guideline to dermatologists, allergologists, biochemists and toxicologists. |
Contents
6 | 3-6 |
Isolation and Identification of Contact Allergens | 3-37 |
References | 3-38 |
The Practical Approach | 4-9 |
References | 4-25 |
Chapter8 StructureActivity Relationships for Contact | 4-34 |
References | 4-41 |
Storage | 7-9 |
Relationships | 7-17 |
Other editions - View all
Allergic Contact Dermatitis: The Molecular Basis Jean-Pierre Lepoittevin,David A. Basketter,An Goossens,Ann-Therese Karlberg No preview available - 2011 |
Common terms and phrases
abietic acid absorption allergenic activity allergic contact dermatitis allylglycidylether analysis analyzed antigenpresenting antigens atomic orbitals Basketter carbon atom Chem chemical structure chloramphenicol chromatography classII colophony colophony components column compounds contact allergens contact sensitivity Coordination Bonds corticosteroids covalent bond crossreactivity cytochrome cytochrome P450 isoenzymes cytokines dehydroabietic acid derivatives Dermatol detected diastereomers dlimonene electronic configuration electrophilic eluting enantiomers enzymes epidermal epoxy ester eugenol example formaldehyde formation formed Gäfvert geometry groups hapten HPLC hydrogen hydroperoxides hydrophobic identified Immunol induced interactions inthe ionization ions isothiazolinones Karlberg AT keratinocytes Langerhans cells Lepoittevin lymphocytes maleopimaric acid mechanism metabolism methods methyl microsomes molecular molecules Nilsson JLG Nucleophilic substitution ofthe patch testing patients peptide periodic table peroxide phase polar protein protons Pulp QSAR radical react reaction reactivity receptor reductase resin acids Roberts DW rosin sample sensitisation potential shell silica skin sensitisation solvent specific structural alert structureactivity studies Toxicol transferases unsaturated